J Korean Soc Biol Psychiatry.  1998 Jun;5(1):134-137.

A Case of Antipsychotic-Regression Syndrome in Haloperidol Treated Tourette's Syndrome

• Jeong HY
• Cho HJ
• Kwon YJ
• Park IJ
• Jin HH

Abstract

Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndromes(TS). In this case, 14 years old boys developed attention deficit symptoms during his infancy. At 4th grade of primary school, he developed vocal tic, motor tic, and coprolalia. With 5mg/day of haloperidol treatment his symptoms of TS were subsided. During the treatment, he developed features of separation anxiety disorder, including dependence, pleading, clinging, and sadness. Symptoms of attention deficit and separation anxiety disorder were improved by 25mg/day of imipramine treatment. During haloperidol treatment of TS, careful observation may be needed whether separation anxiety disorder-like symptom develops.

MeSH Terms

Adolescent
Anxiety, Separation
Haloperidol*
Humans
Imipramine
Tics
Tourette Syndrome*
Haloperidol
Imipramine