J Korean Radiol Soc.  2002 Jul;47(1):15-20. 10.3348/jkrs.2002.47.1.15.

Comparison of Orbital Pseudotumor and Lymphoma: Clinical and Radiological Findings

Affiliations
  • 1Department of Diagnostic Radiology, Research Institute of Radiological Science, Korea. dikim@yumc.yonsei.ac.kr
  • 2Department of Diagnostic Radiology, Yonsei University, College of Medicine, Yonsei University, Korea.

Abstract

PURPOSE: To compare the clinical and radiological findings of orbital pseudotumor with those of orbital lymphoma.
MATERIALS AND METHODS
The clinical and radiological features of 12 orbital pseudotumors were compared with those of 17 orbital lymphomas, the nature of all lesions being confirmed by tissue biopsy. Twenty-four CT scans and nine MR images were retrospectively reviewed and compared, with special focus on the location of a tumor in the orbit, the invasion of periorbital structures, tumor margin, bilaterality, and signal intensity. The initial symptoms at admission were also classified and compared.
RESULTS
In 50% of cases, orbital pseudotumors were located in both extraconal and intraconal space; 75% involved two or more extraocular muscles, and 33% involved the optic nerve. Margins were either infiltrative (75%) or ill-defined (92%). As for orbital lymphomas, 64% occupied extraconal space, invading one or less extraocular muscle (76%) and conjunctiva (29%). Seventy-one percent had a sharp margin, and 65% were lobulated or round. In pseudotumors, orbital pain and visual loss were major symptoms, while in lymphomas a painless orbital mass was the initial symptom.
CONCLUSION
CT or MR image analysis of lesion location, margin, and the involvement of adjacent extra-ocular muscle or optic nerves may help differentiate between orbital lymphoma and orbital pseudo tumor.

Keyword

Orbit, CT; Orbit, MR; Orbit, inflammation; Orbit, neoplasms

MeSH Terms

Biopsy
Conjunctiva
Lymphoma*
Muscles
Optic Nerve
Orbit*
Orbital Pseudotumor*
Retrospective Studies
Tomography, X-Ray Computed
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