J Korean Rheum Assoc.  2000 Dec;7(4):415-420.

A Case of Crohn? Disease Associated with Pyoderma Gangrenosum and Peripheral Arthritis

Affiliations
  • 1Department of Internal Medicine, Inha University College of Medicine, Inchon, Korea.

Abstract

The Crohn? disease is a inflammatory bowel disease and it? symptoms are nonspecific. The extraintestinal manifestations of Crohn? disease are arthritis, pericholangitis, erythema nodosum, pyoderma gangrenosum, uveitis, episcleritis, and miscellaneous. Arthritic manifestations caused by Crohn? disease belong to seronegative spondyloarthropathies and are divided into peripheral arthritis, spondylitis, and sacroiliitis. And peripheral arthritis in Crohn? disease usually worsen with exacerbation of bowel inflammation but pyoderma gangrenosum, the most severe skin lesion, bears little relationship to the activity or extent of the colitis. A 53 year-old man presented peripheral arthritis on multiple joints and necrotizing ulcerative skin lesion on abdomen and left knee. He had undergone T-loop colostomy due to recurrent anal fistula. Colonoscopy and biopsy of colonic mucosa showed Crohn? disease. We report a case of Crohn? disease associated with pyoderma gangrenosum and peripheral arthritis with relevant review of literatures.

Keyword

Peripheral arthritis; Crohn? disease; Pyoderma gangrenosum

MeSH Terms

Abdomen
Arthritis*
Biopsy
Colitis
Colon
Colonoscopy
Colostomy
Erythema Nodosum
Humans
Inflammation
Inflammatory Bowel Diseases
Joints
Knee
Middle Aged
Mucous Membrane
Pyoderma Gangrenosum*
Pyoderma*
Rectal Fistula
Sacroiliitis
Scleritis
Skin
Spondylarthropathies
Spondylitis
Ulcer
Uveitis
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