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Arterial thrombosis of the lower extremity following total hip replacement is a rare but serious complication that threatens the lower limb and sometimes the life of the patient. We report two cases of an arterial occlusion after total hip arthroplasty. The cause of the occlusion is believed to be a thromboembolism in elderly patients due to underlying artherosclerosis. In the case of multifocal artherosclerosis, a vein graft is not feasible and an infusion of a thrombolytic drug is the optimal treatment. However, the result of this method varies.