Cancer Res Treat.  2012 Dec;44(4):275-278.

Mucoepidermoid Carcinoma in The External Auditory Canal: A Case Report

• Chung JH
• Lee SH
• Park CW
• Tae K

Abstract

Mucoepidermoid carcinoma in the external auditory canal is extremely rare. Strategies used for treatment of mucoepidermoid carcinoma remain controversial. We present a case of mucoepidermoid carcinoma of the external auditory canal. The patient underwent lateral temporal bone resection and the surgical defect was obliterated with temporal muscle. He is currently disease-free, four years after surgery. Proper diagnostic measures and strategy for treatment of mucoepidermoid carcinoma are discussed.

Keyword

Mucoepidermoid carcinoma; Ear canal; Temporal bone

MeSH Terms

Carcinoma, Mucoepidermoid
Ear Canal
Humans
Temporal Bone
Temporal Muscle

Figure

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  Fig. 1 Otoscopic findings of the left ear (A) and pathologic findings (B, C). (A) A pinkish mass was observed at the postero-superior portion of the external auditory canal. Normal tympanic membrane was observed. (B) Immunohistochemical staining of p63 revealed staining of the basal cell layer of epithelium (×100). (C) Immunohistochemical staining of cytokeratin 20 showed staining of cytoplasm of mucinous cells (×200).

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  Fig. 2 Temporal bone computed tomography (CT) with contrast enhancement (A) and fluorine-18 fluorodeoxyglucose (F-18 FDG) positron emission tomography/CT scan (B). (A) A well-enhanced protruding skin lesion measuring 1.2 cm was observed at the postero-superior aspect of the external auditory canal. (B) Faint F-18 FDG uptake in the left external auditory canal was observed. The peak standard uptake value was 1.12. No distant metastasis was observed.

Reference

1. Bared A, Dave SP, Garcia M, Angeli SI. Mucoepidermoid carcinoma of the external auditory canal (EAC). Acta Otolaryngol. 2007; 127:280–284. PMID: 17364365.

2. Rancic D, Nihailovic D, Mijovic Z. Mucoepidermoid carcinoma of the external auditory canal: case report. Arch Oncol. 2003; 11:27–29.

3. Magliulo G, Fusconi M, Pulice G. Mucoepidermoid carcinoma of the external auditory canal: case report. Am J Otolaryngol. 2003; 24:274–277. PMID: 12884224.

4. Magliulo G, Ciniglio Appiani M. Mucoepidermoid carcinoma of the external auditory canal. Otolaryngol Head Neck Surg. 2010; 142:624–625. PMID: 20304291.

5. Yoon YH, Park HT, Kim EH, Park YH. A case of mucoepidermoid carcinoma occurring in external auditory canal. Korean J Otorhinolaryngol-Head Neck Surg. 2008; 51:822–824.

6. Arriaga M, Curtin H, Takahashi H, Hirsch BE, Kamerer DB. Staging proposal for external auditory meatus carcinoma based on preoperative clinical examination and computed tomography findings. Ann Otol Rhinol Laryngol. 1990; 99(9 Pt 1):714–721. PMID: 2396807.

7. Marsh M, Jenkins H. Cummings CW, Flint PW, Harker LA, Haughey BH, Richardson MA, Robbins KT, editors. Temporal bone neoplasms and lateral cranialbase surgery. Cummings otolaryngology: head and neck surgery. 2005. 4th ed. St. Louis: Elsevier Mosby;p. 3699–3737.