Yonsei Med J.  2013 Nov;54(6):1454-1462. 10.3349/ymj.2013.54.6.1454.

Factors Associated with Treatment Outcomes in Mindfulness-Based Cognitive Therapy for Panic Disorder

• Kim B
• Cho SJ
• Lee KS
• Lee JY
• Choe AY
• Lee JE
• Choi TK
• Lee SH

• KMID: 1798143
• DOI: http://doi.org/10.3349/ymj.2013.54.6.1454

Abstract

PURPOSE
Although the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) for panic disorder (PD) has been studied previously, data on the predictors of treatment outcomes in MBCT for PD are scarce.
MATERIALS AND METHODS
Eighty patients with PD were screened to analyze treatment outcomes such as MBCT completion, treatment response, and remission after undergoing MBCT for PD. Sociodemographic characteristics, comorbid personality disorders, and baseline medication doses were examined. The study administered the Panic Disorder Severity Scale, Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale and Anxiety Sensitivity Inventory-Revised to patients at baseline and at eight weeks.
RESULTS
Sixty-five participants were enrolled in the present study. Comorbid personality disorder was significantly associated with MBCT non-completion. We found that anxiety sensitivity (AS) improvement after an eight week MBCT program was a statistically significant factor associated with treatment response. Using logistic regression analysis, AS improvement after MBCT showed significant association with PD remission after MBCT.
CONCLUSION
Comorbid personality disorders of participants could be a potential predictor of MBCT non-completion. Furthermore, AS improvement after MBCT may predict treatment response and remission after MBCT for PD. However, better designed studies with a larger number of patients are needed to confirm our findings.

Keyword

Mindfulness-Based Cognitive Therapy; panic disorder; treatment outcome; anxiety sensitivity; comorbid personality disorder

MeSH Terms

Adult
Cognitive Therapy/*methods
Female
Humans
Male
Middle Aged
Mindfulness/*methods
Panic Disorder/*therapy
Socioeconomic Factors
Young Adult

Figure

• 

  Fig. 1 Flow diagram of the study of MBCT for panic disorder. MBCT, Mindfulness-Based Cognitive Therapy; PD, panic disorder; PDSS, Panic Disorder Severity Scale; HAM-D, Hamilton Depression Rating Scale; HAM-A, Hamilton Anxiety Rating Scale.

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