J Korean Med Sci.  2009 Feb;24(1):13-19. 10.3346/jkms.2009.24.1.13.

Physical Activity and Physical Fitness as Predictors of All-Cause Mortality in Korean Men

• Park MS
• Chung SY
• Chang Y
• Kim K

• KMID: 1794400
• DOI: http://doi.org/10.3346/jkms.2009.24.1.13

Abstract

We examined the associations between physical activity (PA), fitness and all-cause mortality and compared their contributions, taking smoking status into consideration. A retrospective cohort study of 18,775 men was carried out between May 1995 and December 2003. Fitness was measured by maximum oxygen uptake and regular PA was defined as at least three times a week, for more than 30 min of leisure time PA. During the mean 6.4 yr of follow-up, 547 deaths were recorded. The hazard ratio (HR) (95% confidence interval [CI]) of regular PA for all-cause mortality was 0.63 (0.52-0.76). The HRs (95% CIs) for men with middle and highest tertile levels of fitness were decreased by 0.58 (0.47-0.70) and 0.58 (0.45-0.75) in comparison to men with lowest one. The inverse association between fitness and mortality was significant among the men who did not engage in regular PA, but not among those who did (p for interaction=0.031). Smoking status did not influence on the associations between regular PA, fitness and mortality. Our result suggested that regular PA and fitness predicted mortality in men. The influence of fitness on mortality was pronounced in the men who did not engage in regular PA.

Keyword

Motor Activity; Exercise; Physical Fitness; Mortality, Smoking

MeSH Terms

Adult
Aged
Asian Continental Ancestry Group
Cardiovascular Diseases/mortality
Cohort Studies
Humans
Korea
Male
Middle Aged
*Mortality
*Motor Activity
Multivariate Analysis
Neoplasms/mortality
Oxygen Consumption
*Physical Fitness
Predictive Value of Tests
Retrospective Studies
Smoking

Reference

1. Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med. 2002. 346:793–801.

2. Gulati M, Pandey DK, Arnsdorf MF, Lauderdale DS, Thisted RA, Wicklund RH, Al-Hani AJ, Black HR. Exercise capacity and the risk of death in women: the St James Women Take Heart Project. Circulation. 2003. 108:1554–1559.

3. NIH Consensus Development Panel on Physical Activity and Cardiovascular Health. Physical activity and cardiovascular health. JAMA. 1996. 276:241–246.

4. Goraya TY, Jacobsen SJ, Pellikka PA, Miller TD, Khan A, Weston SA, Gersh BJ, Roger VL. Prognostic value of treadmill exercise testing in elderly persons. Ann Intern Med. 2000. 132:862–870.

5. Dvorak RV, Tchernof A, Starling RD, Ades PA, DiPietro L, Poehlman ET. Respiratory fitness, free living physical activity, and cardiovascular disease risk in older individuals: a doubly labeled water study. J Clin Endocrinol Metab. 2000. 85:957–963.

6. LaPorte RE, Adams LL, Savage DD, Brenes G, Dearwater S, Cook T. The spectrum of physical activity, cardiovascular disease and health: epidemiologic perspective. Am J Epidemiol. 1985. 120:507–517.

7. Taylor HL, Jacobs DR Jr, Schucker B, Knudsen J, Leon AS, Debacker G. A questionnaire for the assessment of leisure time physical activities. J Chronic Dis. 1978. 31:741–755.

8. Myers J, Kaykha A, George S, Abella J, Zaheer N, Lear S, Yamazaki T, Froelicher V. Fitness versus physical activity patterns in predicting mortality in men. Am J Med. 2004. 117:912–918.

9. Blair SN, Kohl HW 3rd, Paffenbarger RS Jr, Clark DG, Cooper KH, Gibbons LW. Physical fitness and all-cause mortality A prospective study of healthy men and women. JAMA. 1989. 262:2395–2401.

10. Ekelund LG, Haskell WL, Johnson JL, Whaley FS, Criqui MH, Sheps DS. Physical fitness as a predictor of cardiovascular mortality in asymptomatic North American men; the Lipid Research Clinics Mortality Follow-up Study. N Engl J Med. 1988. 319:1379–1384.

11. Lakka TA, Venäläinen JM, Rauramaa R, Salonen R, Tuomilehto J, Salonen JT. Relation of leisure time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction in men. N Engl J Med. 1994. 330:1549–1554.

12. Papathanasiou G, Georqakopoulos D, Georgoudis G, Spyropoulos P, Perrea D, Evangelou A. Effects of chronic smoking on exercise tolerance and on heart rate-systolic blood pressure product in young healthy adults. Eur J Cardiovasc Prev Rehabil. 2007. 14:646–652.

13. Fujita K, Takahashi H, Miura C, Ohkubo T, Sato Y, Ugajin T, Kurashima K, Tsubono Y, Tsuji I, Fukao A, Hisamichi S. Walking and mortality in Japan: the Miyagi Cohort Study. J Epidemiol. 2004. 14:S26–S32.

14. Leitzmann MF, Park Y, Blair A, Ballard-Barbash R, Mouw T, Hollenbeck AR, Schatzkin A. Physical activity recommendations and decreased risk of mortality. Arch Intern Med. 2007. 167:2453–2460.

15. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Rochella EJ. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. National Heart, Lung and Blood Institute. National High Blood Pressure Education Program Coordinating Committee. Seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension. 2003. 42:1206–1252.

16. Taylor CB, Coffey T, Berra K, Iaffaldano R, Casey K, Haskell WL. Severn-day activity and self- report compared to a direct measure of physical activity. Am J Epidemiol. 1984. 120:818–824.

17. Miller GJ, Cooper JA, Beckles GL. Cardiorespiratory fitness, all-cause mortality, and the risk of cardiovascular disease in Trinidadian men-the St James survey. Int J Epidemiol. 2005. 34:1387–1394.

18. 2005 Annual report on the cause of death statistics (based on vital registration). National Statistical Office, Korea. Available at: URL: http://www.nso.go.kr/.

19. Hu G, Tuomilehto J, Silventoinen K, Barengo NC, Peltonen M, Jousilahti P. The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47,212 middle aged Finnish men and women. Int J Obes (Lond). 2005. 29:894–902.

20. Jacobs DR Jr, Ainsworth BE, Hartman TJ, Leon AS. A simultaneous evaluation of 10 commonly used physical activity questionnaires. Med Sci Sports Exerc. 1993. 25:81–91.

21. Dvorak RV, Tchernof A, Starling RD, Ades PA, Dipietro L, Poehlman ET. Respiratory fitness, free living physical activity and cardiovascular disease risk in older individuals: a doubly labeled water study. J Clin Endocrinol Metab. 2000. 85:957–963.

22. LaMonte MJ, Blair SN. Physical activity, cardiorespiratory fitness, and adiposity: contributions to disease risk. Curr Opin Clin Nutr Metab Care. 2006. 9:540–546.

23. Pate RR, Pratt M, Blair SN, Haskell WL, Macera CA, Bouchard C, Buchner D, Ettinger W, Heath GW, King AC. Physical activity and public health. A recommendation from the centers for disease control and prevention and the American college of sports medicine. JAMA. 1995. 273:402–407.

24. U.S. Department of Health and Human Services. Physical activity and health: a report of the surgeon general. 1996. Washington, D.C.: U.S. Department of Health and Human Services.

25. Yang YJ, Yoon YS, Oh SW, Lee ES. The amount of physical activity of Korean adults measured from the 2001 Korean national health and nutrition survey. J Korean Acad Fam Med. 2005. 26:22–30.

26. Jee SH, Samet JM, Ohrr H, Kim JH, Kim IS. Smoking and cancer risk in Korean men and women. Cancer Causes Control. 2004. 15:341–348.

27. Convertino VA. Blood volume response to physical activity and inactivity. Am J Med Sci. 2007. 334:72–79.

28. Oguma Y, Sesso HD, Paffenbarger RS Jr, Lee IM. Physical activity and all-cause mortality in women: a review of the evidence. Br J Sports Med. 2002. 36:162–172.

29. Rockhill B, Willett WC, Manson JE, Leitzmann MF, Stampfer MJ, Hunter DJ, Colditz GA. Physical activity and mortality: a prospective study among women. Am J Public Health. 2001. 91:578–583.

30. Andersen LB, Schnohr P, Schroll M, Hein HO. All-cause mortality associated with physical activity during leisure time,work, sports, and cycling to work. Arch Intern Med. 2000. 160:1621–1628.