Korean J Ophthalmol.  2014 Apr;28(2):155-158. 10.3341/kjo.2014.28.2.155.

Ocular Findings in Children with Single Umbilical Artery: A Case Series of 14 Children

Affiliations
  • 1Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. hjm@snu.ac.kr
  • 2Department of Obsterics & Gynecology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Abstract

PURPOSE
Single umbilical artery (SUA) is the most common malformation of the umbilical cord. However, there have been no studies on the ocular findings in SUA, except for one case report. This study aimed to investigate the ocular findings in children with SUA.
METHODS
Fourteen children (eight boys and six girls) with SUA were evaluated retrospectively. All children underwent a complete ophthalmologic examination.
RESULTS
The prevalence of abnormal ocular findings in children was up to 42.9%. Refractive errors are detected in four eyes (14.3%): myopia > or =-1.50 diopters (D) in one eye (3.6%) and hyperopia > or =+2.00 D in three eyes (10.7%). Epiblepharon was found in three children (21.4%), and strabismus was detected in one child (7.1%).
CONCLUSIONS
Approximately half of the children with SUA showed abnormal ocular findings, therefore, our case series highlight the need for a comprehensive ocular examination and larger prospective research studies in young patients with SUA.

Keyword

Child; Ocular finding; Single umbilical artery

MeSH Terms

Child, Preschool
Eyelid Diseases/*congenital/epidemiology
Eyelids/*abnormalities
Female
Humans
Hyperopia/diagnosis/*epidemiology
Infant
Male
Myopia/diagnosis/*epidemiology
Prevalence
Republic of Korea/epidemiology
Retrospective Studies
Single Umbilical Artery/*epidemiology
Strabismus/*epidemiology
Umbilical Arteries/*abnormalities
Epiblepharon of Upper Lid

Reference

1. Monie IW. Genesis of single umbilical artery. Am J Obstet Gynecol. 1970; 108:400–405.
2. Bryan EM, Kohler HG. The missing umbilical artery. I. Prospective study based on a maternity unit. Arch Dis Child. 1974; 49:844–852.
3. Byrne J, Blanc WA. Malformations and chromosome anomalies in spontaneously aborted fetuses with single umbilical artery. Am J Obstet Gynecol. 1985; 151:340–342.
4. Scalercio F, Ferraro M, Mastrantonio P, Scalercio A. Single umbilical artery (SUA) and congenital eye abnormalities: 2 case reports. Minerva Pediatr. 1998; 50:141–144.
5. Choi KS, Han YK, Park SH, Shin HH. Ophthalmic examinations in premature infants at 3 years of age. J Korean Ophthalmol Soc. 2000; 41:965–972.
6. Noda S, Hayasaka S, Setogawa T. Epiblepharon with inverted eyelashes in Japanese children. I. Incidence and symptoms. Br J Ophthalmol. 1989; 73:126–127.
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