J Korean Med Sci.
2010 Sep;25(9):1372-1374. 10.3346/jkms.2010.25.9.1372.
Acute Kidney Injury due to Menstruation-related Disseminated Intravascular Coagulation in an Adenomyosis Patient: A Case Report
- Affiliations
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- 1Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. dongwonlee@pusan.ac.kr
- 2Division of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
- 3Division of Infectious Disease, Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea.
- 4Medical Research Institute, Pusan National University School of Medicine, Busan, Korea.
- KMID: 1785920
- DOI: http://doi.org/10.3346/jkms.2010.25.9.1372
Abstract
- The authors report a case of acute kidney injury (AKI) resulting from menstruation-related disseminated intravascular coagulation (DIC) in an adenomyosis patient. A 40-yr-old woman who had received gonadotropin for ovulation induction therapy presented with anuria and an elevated serum creatinine level. Her medical history showed primary infertility with diffuse adenomyosis. On admission, her pregnancy test was negative and her menstrual cycle had started 1 day previously. Laboratory data were consistent with DIC, and it was believed to be related to myometrial injury resulting from heavy intramyometrial menstrual flow. Gonadotropin is considered to play an important role in the development of fulminant DIC. This rare case suggests that physicians should be aware that gonadotropin may provoke fulminant DIC in women with adenomyosis.
Keyword
MeSH Terms
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Acute Kidney Injury/*diagnosis/etiology
Adult
Creatinine/blood
Disseminated Intravascular Coagulation/*chemically induced/complications
Endometriosis/*complications/diagnosis/surgery
Female
Fertilization in Vitro
Gonadotropins/*adverse effects
Humans
Magnetic Resonance Imaging
Menstruation/*physiology
Uterus/pathology/surgery
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