J Korean Med Sci.  2008 Aug;23(4):657-661. 10.3346/jkms.2008.23.4.657.

Serum Anti-Mullerian Hormone and Inhibin B Levels at Ovulation Triggering Day Can Predict the Number of Immature Oocytes Retrieved in In Vitro Fertilization Cycles

• Jee BC
• Ku SY
• Suh CS
• Kim KC
• Lee WD
• Kim SH
• Seoul National University College of Medicine Assisted Reproductive Technology (SMART) Study Group

• KMID: 1785825
• DOI: http://doi.org/10.3346/jkms.2008.23.4.657

Abstract

The aim of this study was to investigate whether serum levels of anti-Mullerian hormone (AMH) and inhibin B at ovulation triggering day correlate with the number of immature oocytes obtained from stimulated in vitro fertilization (IVF) cycles. Fiftynine consecutive cycles of ovarian hyperstimulation and IVF were selected from 45 women who had tubal (n=18) or unexplained infertility (n=27) and obtained at least one oocyte. Serum levels of AMH and inhibin B at ovulation triggering day were measured by enzyme-linked immunosorbent assay (ELISA). Univariate analysis and multiple regressions revealed that serum AMH or inhibin B levels were significantly correlated with immature oocyte count and the correlation coefficients were higher compared to the mature oocyte count. Serum AMH and inhibin B levels on triggering day seems to be more closely related with the immature oocyte count and thus could be good predictors to determine the immature oocyte count in IVF cycle.

Keyword

Anti-Mullerian Hormone; Inhibin B; Immature Oocyte; Fertilization In Vitro

MeSH Terms

Adult
Anti-Mullerian Hormone/*blood
Enzyme-Linked Immunosorbent Assay
Female
*Fertilization in Vitro
Humans
Inhibins/*blood
*Oocyte Retrieval
*Ovulation Induction
Regression Analysis

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