J Korean Med Sci.  2009 Dec;24(6):1200-1202. 10.3346/jkms.2009.24.6.1200.

Pyoderma Gangranosum of the Penis

• Kim TH
• Oh SY
• Myung SC

• KMID: 1783156
• DOI: http://doi.org/10.3346/jkms.2009.24.6.1200

Abstract

We report a patient who developed pyoderma gangrenosum in the penis with invasion of the distal urethra. The patient was treated with prednisolone and thalidomide, followed by a reconstructive surgical repair using a scrotal island flap. We report this case with a brief review of the literature.

Keyword

Pyoderma Gangrenosum; Penis

MeSH Terms

Anti-Inflammatory Agents/therapeutic use
Female
Humans
Immunosuppressive Agents/therapeutic use
Male
Middle Aged
*Penile Diseases/drug therapy/pathology/surgery
Penis/*pathology
Prednisolone/therapeutic use
*Pyoderma Gangrenosum/drug therapy/pathology/surgery
Thalidomide/therapeutic use
Treatment Outcome

Figure

• 

  Fig. 1 There are painful purulent ulcerations on the distal dorsal penile shaft and glans of the penis with meatal stenosis and multiple urethrocutaneous fistula.

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  Fig. 2 Histologic findings of the skin lesion. Inflammatory cells infiltrate to the ulcerated dermis (H&E stain, original magnification ×100).

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  Fig. 3 After medical treatment, the skin ulceration improved with re-epithelialization. However, the penile deformity (dorsal curvature) aggravated, which was indicative for an early reconstructive operation.

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  Fig. 4 Intraoperative findings. (A, B) The necrotic tissue was excised and the skin defects of the glans and distal shaft were repaired with a scrotal island flap. Urethral and suprapubic catheterization were performed. (C) There were no urethrocutaneous fistulas without recurrence of pyoderma gangrenosum throughout the postoperative 90 days.

Reference

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