Korean J Intern Med.  2005 Sep;20(3):268-273. 10.3904/kjim.2005.20.3.268.

Clear Cell Hepatocellular Carcinoma with Spontaneous Regression of Primary and Metastatic Lesions

• Jeon SW
• Lee MK
• Lee YD
• Seo HE
• Cho CM
• Tak WY
• Kweon YO

• KMID: 1782243
• DOI: http://doi.org/10.3904/kjim.2005.20.3.268

Abstract

The prognosis of advanced hepatocellular carcinoma (HCC) tends to be poor. Spontaneous regression of this lesion is extremely rare. In this report, we describe a case of HCC which spontaneously regressed along with a metastatic lesion of the chest wall. A huge HCC in the right lobe, the largest diameter of which was about 15x12 cm, developed in a 72-year-old man. He and his family refused further treatment. Three months after the diagnosis, metastasis to the chest wall was detected. We prescribed a painkiller for him in order to alleviate chest pain. Fourteen months after the diagnosis, the tumor size of the primary lesion was downsized to 3x4 cm in diameter. A biopsy taken from the chest wall proved to be clear cell HCC (CHCC). Since then, the metastatic lesion has also disappeared. Here, we report this unusual histologically proven CHCC with literature reviews.

Keyword

Carcinoma; Hepatocellular; Neoplasm regression; Spontaneous

MeSH Terms

Time Factors
Thoracic Wall/pathology
Thoracic Neoplasms/*secondary
Prognosis
*Neoplasm Regression, Spontaneous
Neoplasm Metastasis
Male
Liver Neoplasms/*pathology
Humans
Carcinoma, Hepatocellular/*pathology
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