J Korean Med Sci.  2009 Oct;24(5):795-799. 10.3346/jkms.2009.24.5.795.

The Effects of Short-duration Exercise on Arterial Stiffness in Patients with Stable Coronary Artery Disease

• Sung J
• Yang JH
• Cho SJ
• Hong SH
• Huh EH
• Park SW

• KMID: 1781996
• DOI: http://doi.org/10.3346/jkms.2009.24.5.795

Abstract

Arterial stiffness is an important contributor to the development of cardiovascular disease. We investigated the effect of short duration exercise using the treadmill test on arterial stiffness in the presence of coronary artery disease. We enrolled patients with and without coronary artery diseases (CAD and control group, 50 patients each) referred for treadmill testing. Brachial-ankle pulse wave velocity (baPWV) were measured before and after treadmill testing. Values of baPWV were significantly reduced at 10 min after exercise in both groups, more in the CAD group than in the control group (baseline baPWV and post-exercise change [cm/sec]: 1,527+/-245 and -132+/-155 in the CAD group, 1,439+/-202 and -77+/-93 in the control group, respectively, P for change in each group <0.001, P for difference in changes between the two groups <0.001). These findings persisted after adjusting for age, body mass index, systolic blood pressure, mean arterial pressure (MAP), MAP decreases, and baseline baPWV. Significant post-exercise baPWV reductions were observed in both groups, and more prominently in the CAD group. This finding suggests that short-duration exercise may effectively improve arterial stiffness even in patients with stable coronary artery disease.

Keyword

Exercise; Coronary Artery Disease; Brachial Artery

MeSH Terms

Adult
Aged
Ankle/blood supply
Ankle Brachial Index
Arteries/*physiopathology
Blood Flow Velocity
Brachial Artery/physiology
Coronary Artery Disease/diagnosis/*physiopathology/therapy
Elasticity
*Exercise Therapy
Female
Humans
Male
Middle Aged
Predictive Value of Tests

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