Yonsei Med J.  2007 Apr;48(2):270-273. 10.3349/ymj.2007.48.2.270.

Percutaneous Treatment of Renal Cysts with OK-432 Sclerosis

• Choi YD
• Cho SY
• Cho KS
• Lee DH
• Lee SH

• KMID: 1779530
• DOI: http://doi.org/10.3349/ymj.2007.48.2.270

Abstract

PURPOSE
The aim of this study was to demonstrate OK- 432 sclerotherapy efficacy for treatment of simple renal cysts. MATERIALS AND METHODS: Twenty patients with 25 symptomatic or large simple cysts were treated by ultrasonography (US)-guided percutaneous aspiration and injection of OK-432 (8 men and 12 women, mean age 63.6 years, SD 9.5). Six patients presented with flank pain, 14 presented with renal mass; renal cyst location was right, left, or bilateral sided in 9, 8, and 8 kidneys, respectively. Patients were evaluated by clinical assessment, US, or CT scan 3 months following the procedure. Complete and partial success was defined as symptom resolution with either total cyst ablation or greater than 70% reduction, respectively. Failure was defined as 30% of cyst size recurrence and/or persistent symptoms. RESULTS: Average reduction was 93.0%. Complete and partial resolution occurred in 11 (44.0%) and 13 (52.0%) cysts, respectively. One case was defined as failure, with a 64.2% size reduction from 10.9cm to 3.9cm (volume reduction rate 95.4%). Renal pain improved in all patients, regardless of complete or partial resolution. Minor complications occurred in 3 patients, 2 developed leukocytosis and 1 had mild fever (< 38.5 degrees C) following aspiration and sclerotherapy. Successful treatment was achieved with conservative measures and NSAID therapy. CONCLUSION: Percutaneous treatment of simple renal cysts with OK-432 sclerotherapy was found to be a safe, effective and minimally invasive procedure.

Keyword

Renal cyst; percutaneous sclerotherapy; OK-432

MeSH Terms

Treatment Outcome
*Sclerotherapy/adverse effects
Picibanil/*therapeutic use
Middle Aged
Male
Kidney Diseases, Cystic/pathology/*therapy
Humans
Functional Laterality
Female
Aged
Adult

Figure

• 

  Fig. 1 Imaging of a 47-year-old woman with flank pain. (A) Choronal MRI shows a simple right renal cyst with diameter of 5.8cm. (B) 3 months after percutaneous sclerotherapy with OK-432, CT image shows no remnant of cyst.

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