J Korean Med Sci.  2013 Dec;28(12):1788-1795. 10.3346/jkms.2013.28.12.1788.

Cross-Cultural Adaptation of the Korean Version of the Minneapolis-Manchester Quality of Life Instrument-Adolescent Form

Affiliations
  • 1Center for Pediatric Oncology, National Cancer Center, Goyang, Korea.
  • 2Cancer Policy Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
  • 3Department of Family Medicine & Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
  • 4Cancer Survivorship Clinic, Seoul National University Cancer Hospital, Seoul, Korea.
  • 5Korea Childhood Leukemia Foundation, Seoul, Korea.
  • 6Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • 7Cancer Research Institute, Seoul National University Hospital and College of Medicine, Seoul, Korea.
  • 8Cancer Biostatistics Branch, National Cancer Research Institute, National Cancer Center, Goyang, Korea.
  • 9Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • 10Department of Pediatrics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. hyshin@snu.ac.kr

Abstract

We verified the reliability and validity of the Korean version of the Minneapolis-Manchester Quality of Life Instrument-Adolescent Form (KMMQL-AF) among Korean childhood cancer survivors. A total of 107 childhood cancer patients undergoing cancer treatment and 98 childhood cancer survivors who completed cancer treatment were recruited. To assess the internal structure of the KMMQL-AF, we performed multi-trait scaling analyses and exploratory factor analysis. Additionally, we compared each domains of the KMMQL-AF with those of the Karnofsky Performance Status Scale and the Revised Children's Manifest Anxiety Scale (RCMAS). Internal consistency of the KMMQL-AF was sufficient (Cronbach's alpha: 0.78-0.92). In multi-trait scaling analyses, the KMMQL-AF showed sufficient construct validity. The "physical functioning" domain showed moderate correlation with Karnofsky scores and the "psychological functioning" domain showed moderate-to-high correlation with the RCMAS. The KMMQL-AF discriminated between subgroups of different adolescent cancer survivors depending on treatment completion. The KMMQL-AF is a sufficiently reliable and valid instrument for measuring quality of life among Korean childhood cancer survivors.

Keyword

Quality of Life; Questionnaires; Validation Studies; Child Psychology; Neoplasms; Survivors

MeSH Terms

*Adaptation, Psychological
Adolescent
Antineoplastic Agents/therapeutic use
Asian Continental Ancestry Group
Factor Analysis, Statistical
Female
Humans
Interviews as Topic
Male
Neoplasms/drug therapy/*psychology
Program Evaluation
*Quality of Life
Questionnaires/standards
Republic of Korea
Young Adult
Antineoplastic Agents
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