Cross-Cultural Adaptation of the Korean Version of the Minneapolis-Manchester Quality of Life Instrument-Adolescent Form
- Affiliations
-
- 1Center for Pediatric Oncology, National Cancer Center, Goyang, Korea.
- 2Cancer Policy Branch, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
- 3Department of Family Medicine & Health Promotion Center, Seoul National University Hospital, Seoul, Korea.
- 4Cancer Survivorship Clinic, Seoul National University Cancer Hospital, Seoul, Korea.
- 5Korea Childhood Leukemia Foundation, Seoul, Korea.
- 6Research Institute and Hospital, National Cancer Center, Goyang, Korea.
- 7Cancer Research Institute, Seoul National University Hospital and College of Medicine, Seoul, Korea.
- 8Cancer Biostatistics Branch, National Cancer Research Institute, National Cancer Center, Goyang, Korea.
- 9Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
- 10Department of Pediatrics, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. hyshin@snu.ac.kr
Abstract
- We verified the reliability and validity of the Korean version of the Minneapolis-Manchester Quality of Life Instrument-Adolescent Form (KMMQL-AF) among Korean childhood cancer survivors. A total of 107 childhood cancer patients undergoing cancer treatment and 98 childhood cancer survivors who completed cancer treatment were recruited. To assess the internal structure of the KMMQL-AF, we performed multi-trait scaling analyses and exploratory factor analysis. Additionally, we compared each domains of the KMMQL-AF with those of the Karnofsky Performance Status Scale and the Revised Children's Manifest Anxiety Scale (RCMAS). Internal consistency of the KMMQL-AF was sufficient (Cronbach's alpha: 0.78-0.92). In multi-trait scaling analyses, the KMMQL-AF showed sufficient construct validity. The "physical functioning" domain showed moderate correlation with Karnofsky scores and the "psychological functioning" domain showed moderate-to-high correlation with the RCMAS. The KMMQL-AF discriminated between subgroups of different adolescent cancer survivors depending on treatment completion. The KMMQL-AF is a sufficiently reliable and valid instrument for measuring quality of life among Korean childhood cancer survivors.