J Korean Med Sci.  2013 Dec;28(12):1734-1740. 10.3346/jkms.2013.28.12.1734.

The Association Between the Socioeconomic Status and Thyroid Cancer Prevalence; Based on the Korean National Health and Nutrition Examination Survey 2010-2011

Affiliations
  • 1Department of Preventive Medicine, Chosun University Medical School, Gwangju, Korea. jcsw74@chosun.ac.kr

Abstract

The incidence of thyroid cancer has recently increased in most industrialized countries, including Korea. To date, few studies have examined the association between thyroid cancer and socioeconomic status (SES). The current study was based on data collected from a total of 12,276 subjects (5,277 men and 6,999 women) by the Korean National Health and Nutrition Examination Survey (KNHANES) between 2010 and 2011. Univariate and multivariate logistic regression analysis revealed that older age (odds ration [OR], 1.03; 95% confidence interval [CI], 1.00-1.05), being female (OR, 8.16; 95%CI, 2.99-22.24), being overweight (OR, 1.04; 95%CI, 1.01-1.06), monthly household income (OR, 3.27; 95%CI, 1.16-9.20 for medium-highest household income vs lowest household income; OR, 3.30; 95%CI, 1.16-9.34 for highest household income vs lowest household income), educational level (OR, 2.74; 95%CI, 1.16-6.46 for 10-12 yr vs < 7 yr) and alcohol consumption (OR, 1.89; 95%CI 1.08-3.32) were significant risk factors for thyroid cancer. Our results indicate that the recent increase in thyroid cancer is attributable to better early detection rather than to any increase in actual prevalence.

Keyword

Social Class; Thyroid Neoplasms

MeSH Terms

Adult
Age Factors
Aged
Alcohol Drinking
Demography
Female
Humans
Income
Logistic Models
Male
Middle Aged
Multivariate Analysis
*Nutrition Surveys
Odds Ratio
Prevalence
Republic of Korea/epidemiology
Risk Factors
Sex Factors
Socioeconomic Factors
Thyroid Neoplasms/economics/*epidemiology

Figure

  • Fig. 1 The percentage of thyroid cancer patients according to the monthly household income.

  • Fig. 2 The percentage of thyroid cancer patients according to the education level.


Cited by  2 articles

Analysis of Correlation between Thyroid Cancer Incidence and Socioeconomic Status Using 10-year Sample Cohort Database
Seung Up Yang, Hojin Chang, Chi Young Lim
J Endocr Surg. 2019;19(1):25-33.    doi: 10.16956/jes.2019.19.1.25.

Alcohol Intake and Risk of Thyroid Cancer: A Meta-Analysis of Observational Studies
Seung-Hee Hong, Seung-Kwon Myung, Hyeon Suk Kim
Cancer Res Treat. 2017;49(2):534-547.    doi: 10.4143/crt.2016.161.


Reference

1. Colonna M, Grosclaude P, Remontet L, Schvartz C, Mace-Lesech J, Velten M, Guizard A, Tretarre B, Buemi AV, Arveux P, et al. Incidence of thyroid cancer in adults recorded by French cancer registries (1978-1997). Eur J Cancer. 2002; 38:1762–1768.
2. Verkooijen HM, Fioretta G, Pache JC, Franceschi S, Raymond L, Schubert H, Bouchardy C. Diagnostic changes as a reason for the increase in papillary thyroid cancer incidence in Geneva, Switzerland. Cancer Causes Control. 2003; 14:13–17.
3. Reynolds RM, Weir J, Stockton DL, Brewster DH, Sandeep TC, Strachan MW. Changing trends in incidence and mortality of thyroid cancer in Scotland. Clin Endocrinol (Oxf). 2005; 62:156–162.
4. Hodgson NC, Button J, Solorzano CC. Thyroid cancer: is the incidence still increasing? Ann Surg Oncol. 2004; 11:1093–1097.
5. Liu S, Semenciw R, Ugnat AM, Mao Y. Increasing thyroid cancer incidence in Canada, 1970-1996: time trends and age-period-cohort effects. Br J Cancer. 2001; 85:1335–1339.
6. Burgess JR. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982-1997). Thyroid. 2002; 12:141–149.
7. Jung KW, Won YJ, Kong HJ, Oh CM, Seo HG, Lee JS. Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010. Cancer Res Treat. 2013; 45:1–14.
8. International Agency for Research on Cancer. GLOBOCAN 2008. accessed on 21 August 2013. Available at http://globocan.iarc.fr.
9. Schneider AB, Ron E, Lubin J, Stovall M, Gierlowski TC. Dose-response relationships for radiation-induced thyroid cancer and thyroid nodules: evidence for the prolonged effects of radiation on the thyroid. J Clin Endocrinol Metab. 1993; 77:362–369.
10. Thompson DE, Mabuchi K, Ron E, Soda M, Tokunaga M, Ochikubo S, Sugimoto S, Ikeda T, Terasaki M, Izumi S, et al. Cancer incidence in atomic bomb survivors: part II: solid tumors, 1958-1987. Radiat Res. 1994; S17–S67.
11. Franceschi S. Iodine intake and thyroid carcinoma: a potential risk factor. Exp Clin Endocrinol Diabetes. 1998; 106:S38–S44.
12. Goodman MT, Kolonel LN, Wilkens LR. The association of body size, reproductive factors and thyroid cancer. Br J Cancer. 1992; 66:1180–1184.
13. Cote GJ, Wohllk N, Evans D, Goepfert H, Gagel RF. RET proto-oncogene mutations in multiple endocrine neoplasia type 2 and medullary thyroid carcinoma. Baillieres Clin Endocrinol Metab. 1995; 9:609–630.
14. Rossing MA, Cushing KL, Voigt LF, Wicklund KG, Daling JR. Risk of papillary thyroid cancer in women in relation to smoking and alcohol consumption. Epidemiology. 2000; 11:49–54.
15. Dal Maso L, La Vecchia C, Franceschi S, Preston-Martin S, Ron E, Levi F, Mack W, Mark SD, McTiernan A, Kolonel L, et al. A pooled analysis of thyroid cancer studies: V. anthropometric factors. Cancer Causes Control. 2000; 11:137–144.
16. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA. 2006; 295:2164–2167.
17. Rojeski MT, Gharib H. Nodular thyroid disease: evaluation and management. N Engl J Med. 1985; 313:428–436.
18. Ross DS. J Editorial: predicting thyroid malignancy. J Clin Endocrinol Metab. 2006; 91:4253–4255.
19. Liebeskind A, Sikora AG, Komisar A, Slavit D, Fried K. Rates of malignancy in incidentally discovered thyroid nodules evaluated with sonography and fine-needle aspiration. J Ultrasound Med. 2005; 24:629–634.
20. Enewold L, Zhu K, Ron E, Marrogi AJ, Stojadinovic A, Peoples GE, Devesa SS. Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980-2005. Cancer Epidemiol Biomarkers Prev. 2009; 18:784–791.
21. Fincham SM, Ugnat AM, Hill GB, Kreiger N, Mao Y. Is occupation a risk factor for thyroid cancer? Canadian Cancer Registries Epidemiology Research Group. J Occup Environ Med. 2000; 42:318–322.
22. Levi F, Franceschi S, Te VC, Negri E, Vecchia C. Descriptive epidemiology of thyroid cancer in the Swiss Canton of Vaud. J Cancer Res Clin Oncol. 1990; 116:639–647.
23. Haselkorn T, Bernstein L, Preston-Martin S, Cozen W, Mack WJ. Descriptive epidemiology of thyroid cancer in Los Angeles County, 1972-1995. Cancer Causes Control. 2000; 11:163–170.
24. Iribarren C, Haselkorn T, Tekawa IS, Friedman GD. Cohort study of thyroid cancer in a San Francisco Bay area population. Int J Cancer. 2001; 93:745–750.
25. Sprague BL, Warren Andersen S, Trentham-Dietz A. Thyroid cancer incidence and socioeconomic indicators of health care access. Cancer Causes Control. 2008; 19:585–593.
26. Han MA, Choi KS, Lee HY, Kim Y, Jun JK, Park EC. Current status of thyroid cancer screening in Korea: results from a nationwide interview survey. Asian Pac J Cancer Prev. 2011; 12:1657–1663.
27. Kim JM, Kim HM, Jung BY, Park EC, Cho WH, Lee SG. The association between cancer incidence and family income: analysis of Korean National Health Insurance cancer registration data. Asian Pac J Cancer Prev. 2012; 13:1371–1376.
28. Kim Y, Lee BK. Associations of blood lead, cadmium, and mercury with estimated glomerular filtration rate in the Korean general population: analysis of 2008-2010 Korean National Health and Nutrition Examination Survey data. Environ Res. 2012; 118:124–129.
29. Kilfoy BA, Zheng T, Holford TR, Han X, Ward MH, Sjodin A, Zhang Y, Bai Y, Zhu C, Guo GL, et al. International patterns and trends in thyroid cancer incidence, 1973-2002. Cancer Causes Control. 2009; 20:525–531.
30. Lee TJ, Kim S, Cho HJ, Lee JH. The incidence of thyroid cancer is affected by the characteristics of a healthcare system. J Korean Med Sci. 2012; 27:1491–1498.
31. Newacheck PW, Hung YY, Park MJ, Brindis CD, Irwin CE Jr. Disparities in adolescent health and health care: does socioeconomic status matter? Health Serv Res. 2003; 38:1235–1252.
32. Lazarus JH. Hyperthyroidism. Lancet. 1997; 349:339–343.
33. Zhang Y, Zhu Y, Risch HA. Changing incidence of thyroid cancer. JAMA. 2006; 296:1350.
34. Lee SH, Kim TY, Ryu JS, Gong G, Kim WB, Kim SC, Hong SJ, Shong YK. Trends analysis of characteristics of thyroid cancer patients in one medical center. J Korean Endocr Soc. 2008; 23:35–43.
Full Text Links
  • JKMS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr