J Korean Med Sci.  2010 Feb;25(2):327-329. 10.3346/jkms.2010.25.2.327.

Malignant Struma Ovarii: A Case Report

• Yucesoy G
• Cakiroglu
• Muezzinoglu B
• Besnili B
• Yucesoy I

• KMID: 1779271
• DOI: http://doi.org/10.3346/jkms.2010.25.2.327

Abstract

We present a case of a 40-yr-old woman diagnosed with a primary malignant struma ovarii. The patient was admitted with the complaint of pelvic pain and a large pelvic mass in the mid-portion of lower abdomen on gynecological examination. Pre-operative tumor markers and routine biochemistry were unremarkable. She was treated with total abdominal hysterectomy and right salpingo-oopherectomy. Post-operatively, she was diagnosed with a malignant struma ovarii through the usage of histopathological criteria similar to the guidelines for primary thyroid gland disease. The patient was subsequently performed left salpingo-oopherectomy and retroperitoneal pelvic lympadenectomy for re-staging. Although, left ovary and lymph nodes were histopathologically normal, she was offered thyroidectomy but she refused to accept the offer. Thyroglobulin level was monitored in the post-operative period. She is free of the disease for 18 months.

Keyword

Struma Ovarii; Thyroglobulin; Whole Body Imaging

MeSH Terms

Adult
Female
Humans
Hysterectomy
Ovarian Neoplasms/*diagnosis/pathology/ultrasonography
Ovariectomy
Struma Ovarii/*diagnosis/pathology/secondary
Thyroglobulin/metabolism
Thyroglobulin

Figure

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  Fig. 1 Non encapsulated small papillary carcinoma within the thyroid tissue (H&E, ×40).

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  Fig. 2 On left side papillary tumor with typical nuclear features contrasting the normal thyroid follicular epithelium (H&E, ×100).

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  Fig. 3 High power view of papillary carcinoma with enlarged, oval, overlapping, ground glass nuclei (H&E, ×200).

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