J Korean Med Sci.  2005 Jun;20(3):373-378. 10.3346/jkms.2005.20.3.373.

Distribution of the Ankle-Brachial Index and Associated Cardiovascular Risk Factors in a Population of Middle-Aged and Elderly Koreans

Affiliations
  • 1Department of Preventive Medicine, Seonam University College of Medicine, Namwon, Korea.
  • 2Department of Preventive Medicine, Chungnam University College of Medicine, Daejeon, Korea.
  • 3Department of Neurology, Chonbuk National University Hospital, Jeonju, Korea.
  • 4Department of Preventive Medicine, Chosun University College of Medicine, Gwangju, Korea.
  • 5Department of Preventive Medicine, Chonnam National University College of Medicine, Chonnam National University Research Center of Medical Sciences, Gwangju, Korea. jschoix@chonnam.ac.kr

Abstract

The Doppler ankle-brachial pressure index (ABI) is an objective and efficient tool that can be used to determine the presence and severity of peripheral arterial disease in the lower extremities. The ABI value is inversely associated with other cardiovascular risk factors. To date, there have been no studies of the distribution of ABI in Korea. We performed a cross-sectional study of 1,943 subjects (681 men and 1,262 women; 45-74 yr old) in Namwon, Korea. The prevalence of a low ABI (<0.90) was 2.2% in men and 1.8% in women, and a high ABI (>or=1.30) was prevalent in 3.1% of men and 0.8% of women. Age, smoking habits, waist circumference, hypertension, and blood pressure were associated with ABI values in both sexes. The presence of carotid plaques was associated with ABI values only in men, whereas pulse pressure was associated with ABI values only in women (p<0.05). Although the prevalence of a low ABI in the present study was lower than those reported previously for Western populations and Japanese men, our results suggest that the ABI might be used as an indicator of cardiovascular risk factors in adult Koreans.

Keyword

Peripheral Vascular Diseases; Prevalence; Ankle-brachial Index; Risk Factors

MeSH Terms

Aged
Analysis of Variance
Ankle/*blood supply
Blood Flow Velocity
Blood Pressure
Brachial Artery/*physiology
Cardiovascular Diseases/blood/etiology/*physiopathology
Cholesterol/blood
Cohort Studies
Cross-Sectional Studies
Diabetes Mellitus, Type 2/complications
Female
Humans
Hypertension/complications
Korea
Lipoproteins, HDL Cholesterol/blood
Male
Middle Aged
Prospective Studies
Risk Factors
Triglycerides/blood

Figure

  • Fig. 1 The distribution of the ankle-brachial index (ABI) values for men (black bars) and women (white bars).


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Reference

1. Hallett JW Jr. Predicting the future of vascular health care: the impact of the baby boom generation. Semin Vasc Surg. 2001. 14:54–63.
Article
2. Mohler ER 3rd. Peripheral arterial disease: identification and implications. Arch Intern Med. 2003. 163:2306–2314.
3. Smith FB, Lee AJ, Price JF, van Wijk MC, Fowkes FG. Changes in ankle brachial index in symptomatic and asymptomatic subjects in the general population. J Vasc Surg. 2003. 38:1323–1330.
Article
4. Zheng ZJ, Sharrett AR, Chambless LE, Rosamond WD, Nieto FJ, Sheps DS, Dobs A, Evans GW, Heiss G. Associations of ankle-brachial index with clinical coronary heart disease, stroke and preclinical carotid and popliteal atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis. 1997. 131:115–125.
Article
5. Schroll M, Munck O. Estimation of peripheral arteriosclerotic disease by ankle blood pressure measurements in a population study of 60-year-old men and women. J Chronic Dis. 1981. 34:261–269.
Article
6. Criqui MH, Denenberg JO, Langer RD, Fronek A. The epidemiology of peripheral arterial disease: importance of identifying the population at risk. Vasc Med. 1997. 2:221–226.
Article
7. Resnick HE, Lindsay RS, McDermott MM, Devereux RB, Jones KL, Fabsitz RR, Howard BV. Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study. Circulation. 2004. 109:733–739.
Article
8. Fabsitz RR, Sidawy AN, Go O, Lee ET, Welty TK, Devereux RB, Howard BV. Prevalence of peripheral arterial disease and associated risk factors in American Indians: the Strong Heart Study. Am J Epidemiol. 1999. 149:330–338.
Article
9. Lamar Welch VL, Casper M, Greenlund K, Zheng ZJ, Giles W, Rith-Najarian S. Prevalence of lower extremity arterial disease defined by the ankle-brachial index among American Indians: the Inter-Tribal Heart Project. Ethn Dis. 2002. 12:63–67.
10. McKenna M, Wolfson S, Kuller L. The ratio of ankle and arm arterial pressure as an independent predictor of mortality. Atherosclerosis. 1991. 87:119–128.
Article
11. McDermott MM, Feinglass J, Slavensky R, Pearce WH. The ankle-brachial index as a predictor of survival in patients with peripheral vascular disease. J Gen Intern Med. 1994. 9:445–449.
Article
12. Newman AB, Sutton-Tyrrell K, Vogt MT, Kuller LH. Morbidity and mortality in hypertensive adults with a low ankle/arm blood pressure index. JAMA. 1993. 270:487–489.
Article
13. Meijer WT, Hoes AW, Rutgers D, Bots ML, Hofman A, Grobbee DE. Peripheral arterial disease in the elderly: The Rotterdam Study. Arterioscler Thromb Vasc Biol. 1998. 18:185–192.
14. Cui R, Iso H, Yamagishi K, Tanigawa T, Imano H, Ohira T, Kitamura A, Sato S, Naito Y, Shimamoto T. Ankle-arm blood pressure index and cardiovascular risk factors in elderly Japanese men. Hypertens Res. 2003. 26:377–382.
Article
15. Nam JH, Park SW, Ahn CW, Song YD, Lim SK, Kim KR, Lee HC, Huh KB. Atherosclerotic severity and risk factors in type 2 diabetic patients with visceral (metabolic) obesity in Korea. J Korean Diabets Assoc. 2001. 25:20–34.
16. Lee YS, Oh HJ, Kang DH, Yoon KI, Choi KB. ABI and risk factors of peripheral vascular disease in maintenance dialysis patients: According to the modality of dialysis. Korean J Nephrol. 2003. 22:722–730.
17. American Society of Hypertension. Recommendations for routine blood pressure measurement by indirect cuff sphygmomanometry. Am J Hypertens. 1992. 5:207–209.
18. Li R, Duncan BB, Metcalf PA, Crouse JR 3rd, Sharrett AR, Tyroler HA, Barnes R, Heiss G. B-mode-detected carotid artery plaque in a general population. Atherosclerosis Risk in Communities (ARIC) Study Investigators. Stroke. 1994. 25:2377–2383.
Article
19. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT Jr, Roccella EJ. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003. 289:2560–2572.
Article
20. Lee DH. Childhood obesity. J Korean Pediatr Soc. 2003. 46:Suppl. 436–450.
21. Greenland P, Abrams J, Aurigemma GP, Bond MG, Clark LT, Criqui MH, Crouse JR 3rd, Friedman L, Fuster V, Herrington DM, Kuller LH, Ridker PM, Roberts WC, Stanford W, Stone N, Swan HJ, Taubert KA, Wexler L. Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III. Circulation. 2000. 101:E16–E22.
22. Meijer WT, Grobbee DE, Hunink MG, Hofman A, Hoes AW. Determinants of peripheral arterial disease in the elderly: the Rotterdam study. Arch Intern Med. 2000. 160:2934–2938.
23. Zimmerman BR, Palumbo PJ, O'Fallon WM, Ellefson RD, Osmundson PJ, Kazmier FJ. A prospective study of peripheral occlusive arterial disease in diabetes. III. Initial lipid and lipoprotein findings. Mayo Clin Proc. 1981. 56:233–242.
24. Lu JT, Creager MA. The relationship of cigarette smoking to peripheral arterial disease. Rev Cardiovasc Med. 2004. 5:189–193.
25. Gibson NE. A low or high ankle brachial index increased the risk for all-cause mortality in Native Americans. ACP J Club. 2004. 141:79.
26. Ross R. Atherosclerosis--an inflammatory disease. N Engl J Med. 1999. 340:115–126.
27. Ouriel K, McDonnell AE, Metz CE, Zarins CK. Critical evaluation of stress testing in the diagnosis of peripheral vascular disease. Surgery. 1982. 91:686–693.
28. Lee CW, Park KY, Son SM, Kim IJ, Kim YK. Usefulness of ankle brachial pressure index measured using photoplethysmography and automated blood pressure measurement device. Korean J Med. 2003. 64:677–681.
29. McDermott MM, Greenland P, Liu K, Guralnik JM, Celic L, Criqui MH, Chan C, Martin GJ, Schneider J, Pearce WH, Taylor LM, Clark E. The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study. Ann Intern Med. 2002. 136:873–883.
Article
30. Belch JJ, Topol EJ, Agnelli G, Bertrand M, Califf RM, Clement DL, Creager MA, Easton JD, Gavin JR 3rd, Greenland P, Hankey G, Hanrath P, Hirsch AT, Meyer J, Smith SC, Sullivan F, Weber MA. Critical issues in peripheral arterial disease detection and management: a call to action. Arch Intern Med. 2003. 163:884–892.
31. O'Hare AM, Feinglass J, Sidawy AN, Bacchetti P, Rodriguez RA, Daley J, Khuri S, Henderson WG, Johansen KL. Impact of renal insufficiency on short-term morbidity and mortality after lower extremity revascularization: data from the Department of Veterans Affairs' National Surgical Quality Improvement Program. J Am Soc Nephrol. 2003. 14:1287–1295.
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