J Korean Med Sci.  2013 Oct;28(10):1461-1467. 10.3346/jkms.2013.28.10.1461.

Association between Central Obesity and Circadian Parameters of Blood Pressure from the Korean Ambulatory Blood Pressure Monitoring Registry: Kor-ABP Registry

• Kang IS
• Pyun WB
• Shin J
• Kim JH
• Kim SG
• Shin GJ

• KMID: 1777682
• DOI: http://doi.org/10.3346/jkms.2013.28.10.1461

Abstract

Central obesity has been reported as a risk for atherosclerosis and metabolic syndrome. The influence of central obesity on diurnal blood pressure (BP) has not been established. In this study, we investigated the influence of central obesity on the circadian parameters of BP by 24 hr ambulatory BP monitoring. Total 1,290 subjects were enrolled from the Korean Ambulatory BP registry. Central obesity was defined as having a waist circumference> or =90 cm in males and > or =85 cm in females. The central-obese group had higher daytime systolic BP (SBP), nighttime SBP and diastolic BP (DBP) than the non-obese group (all, P<0.001). There were no differences in nocturnal dipping (ND) patterns between the groups. Female participants showed a higher BP mean difference (MD) than male participants with concerns of central obesity (daytime SBP MD 5.28 vs 4.27, nighttime SBP MD 6.48 vs 2.72) and wider pulse pressure (PP). Central obesity within the elderly (> or =65 yr) also showed a higher BP MD than within the younger group (daytime SBP MD 8.23 vs 3.87, daytime DBP 4.10 vs 1.59). In conclusion, central obesity has no influence on nocturnal dipping patterns. However, higher SBP and wider PP are associated with central obesity, which is accentuated in women.

Keyword

Obesity, Abdominal; Blood Pressure Monitoring, Ambulatory; Blood Pressure

MeSH Terms

Adult
Age Factors
Aged
Asian Continental Ancestry Group
Blood Pressure/physiology
*Blood Pressure Monitoring, Ambulatory
Circadian Rhythm/*physiology
Female
Humans
Hypertension/*complications/epidemiology
Male
Middle Aged
Obesity, Abdominal/*complications/*epidemiology/pathology
Registries
Republic of Korea/epidemiology
Sex Factors
Waist Circumference

Figure

• 

  Fig. 1 Day and nighttime blood pressure by sub-groups. (A) Daytime systolic BP difference. (B) Daytime diastolic BP difference. (C) Nighttime systolic BP difference. (D) Nighttime diastolic BP difference. *P < 0.01, †P < 0.05. All values were adjusted by age, HTN, DM, dyslipidemia, CHD, stroke, HF and sex. BP, blood pressure; HTN, hypertension; DM, Diabetes mellitus; CHD, coronary heart disease; HF, heart failure.

• 

  Fig. 2 Day and nighttime pulse pressure according sub-groups. (A) Daytime pulse pressure. (B) Night time pulse pressure. *P < 0.01, †P < 0.05, ‡P for interaction < 0.01. All values were adjusted for age, HTN, DM, dyslipidemia, CHD, stroke, HF and sex. HTN, hypertension; DM, Diabetes mellitus; CHD, coronary heart disease; HF, heart failure.

• 

  Fig. 3 Nocturnal dipping pattern.

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