Yonsei Med J.  2006 Dec;47(6):840-846. 10.3349/ymj.2006.47.6.840.

A Comparison of Autologous and Homologous Transfusions in Spinal Fusion

Affiliations
  • 1Departments of Orthopaedic Surgery, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea.
  • 2Departments of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea. hwanlee@yumc.yonsei.ac.kr
  • 3Departments of Orthopaedic Surgery, Korea University, Anam Hospital, Seoul, Korea.

Abstract

Autologous transfusion has been used to overcome adverse effects of homologous transfusion. Clinical studies evaluating general orthopaedic postoperative results have been designed to compare these transfusion methods. However, few studies have evaluated postoperative results in spinal fusion surgeries, which have larger blood loss volumes. The purpose of this study is to determine if there are differences in postoperative infection and clinical results of spinal fusion with autologous, as compared to homologous, blood transfusion. A total of 62 patients who underwent instrumented spinal fusion and received autologous (n = 30) or homologous (n = 32) transfusions were reviewed. Information on gender, age, preoperative and 3-day postoperative hematologic features, total transfused units, segmental estimated blood loss, transfused units, and surgery time were collected. In addition, postoperative infection data on wound infection, pneumonia, urinary tract infection, cellulitis, and viral disease, incidence and duration of fever, as well as clinical results, fusion rates, and patient feedback were collected. No differences in postoperative infection and clinical results were found between the two types of transfusions; however, homologous transfusion was associated with an increased number of total units transfused, longer duration of fever, and decreased patient satisfaction regarding the transfusion.

Keyword

Spinal fusion; autologous transfusion

MeSH Terms

*Spinal Fusion
Postoperative Complications
Middle Aged
Male
Humans
Female
Blood Transfusion, Autologous
*Blood Transfusion
Aged
Adult

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