Korean J Intern Med.  2005 Mar;20(1):105-109. 10.3904/kjim.2005.20.1.105.

Ovarian Granulosa Cell Tumor presenting as Meigs' Syndrome with elevated CA125

Affiliations
  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. llssss.lee@samsung.co.kr
  • 2Department of Pathology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

Herein, a rare case of ovarian granulosa cell tumor, presenting as Meigs' syndrome, with elevated carbohydrate antigen 125 (CA125), is reported. A 69-year-old woman was admitted for the investigation of abdominal fullness and dyspnea. A preoperative examination revealed a huge pelvic tumor and an abdominopelvic magnetic resonance image (MRI) assumed ovarian cancer. A chest computed tomography (CT) scan revealed pleural effusion. A laparotomy confirmed the huge mass to be an ovarian tumor. A total abdominal hysterectomy (TAH), with a bilateral salpingo-oophorectomy (BSO) and partial omentectomy, was performed. Although short-term intrathoracic drainage was required, the hydrothorax and ascites rapidly resolved in the postoperative period.

Keyword

Meigs' syndrome; Granulosa cell tumor; CA125

MeSH Terms

Aged
CA-125 Antigen/*blood
Diagnosis, Differential
Female
Granulosa Cell Tumor/*diagnosis
Humans
Meige Syndrome/*diagnosis
Ovarian Neoplasms/*diagnosis
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