Korean J Gastroenterol.  2010 Jul;56(1):1-5. 10.4166/kjg.2010.56.1.1.

A Spongiform Mass in the Stomach: Pyloric Gland Adenoma with a Transition to Adenocarcinoma

• Oh MG
• Cho SJ
• Lee JH
• Kook MC
• Park SY

• KMID: 1775871
• DOI: http://doi.org/10.4166/kjg.2010.56.1.1

Abstract

No abstract available.

Figure

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  Fig. 1. Endoscopic findings. (A) About 3 cm sized polypoid mass sessile has been detected at gastric fundus. (B) The mass showed cri-briform or sponge-like surface full of tiny holes. Its surface appeared to be greasy with transparent mucus.

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  Fig. 2. Abdominal CT showed a 3.5 cm sized polypoid mass with a short stalk in the gastric fundus. Lymph node involve-ment or distant metastasis was not observed.

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  Fig. 3. Gross findings. (A) Polypoid lesion was detected at the resected stomach. (B) Polypoid mass was connected to the stomach by a short stalk with 1.5 cm sized base.

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  Fig. 4. Microscopic findings. (A) Polypoid mass consisted of cystically dilated tubules which are not fused or irregularly branched (H&E stain, ×1). (B) Epithelial glands except gastric foveolar epithelum were strongly stained for MUC6 (×1). (C) Pyloric gland adenoma was composed of closely packed pyloric gland type tubules with a monolayer of cuboidal columnar epithelial cells containing pale to eosinophilic cytoplasm (white arrow). Pyloric gland adenocarcinoma had a nuclear atypism, ser-rated epithelial arrangement, and focal complex branching of tubules (black arrow) (H&E stain, ×100).

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