Korean J Anesthesiol.  2011 Oct;61(4):281-287. 10.4097/kjae.2011.61.4.281.

Comparison of the central venous pressure from internal jugular vein and the pressure measured from the peripherally inserted antecubital central catheter (PICCP) in liver transplantation recipients

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, Research Institute and Hospital, National Cancer Center, Goyang, Korea. yaeppun@korea.com
  • 2Department of Cancer Registration and Biostatistics Branch, Research Institute and Hospital, National Cancer Center, Goyang, Korea.
  • 3Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.

Abstract

BACKGROUND
Unlike its use during stable conditions, central venous pressure (CVP) monitoring from a peripherally inserted central venous catheter (PICC) has not often been used in surgeries with significant hemodynamic alterations. The aim of this study was to evaluate the feasibility of measuring PICC pressure (PICCP) as an alternative to measuring centrally inserted central catheter pressure (CICCP) in adult liver transplantation (LT) patients.
METHODS
We measured PICCP and CICCP simultaneously during each main surgical period in adult LT. Statistical analysis was performed using simple linear regression analysis to observe whether changes in PICCP paralleled by simultaneous changes in CICCP. Correlation analysis and Bland-Altman analysis were used to determine the degree of agreement between the two devices. Differences were considered statistically significant when P values were less than 0.05.
RESULTS
A total of 1342 data pairs were collected from 35 patients. The PICCPs and CICCPs were highly correlated overall (r = 0.970, P < 0.001) as well as at each period measured. The differences among each period were not clinically significant (0.33 mmHg for pre-anhepatic, 0.32 mmHg for anhepatic, -0.15 mmHg for reperfusion, and -0.10 mmHg for neohepatic periods). The overall mean difference was 0.14 mmHg (95% confidence interval: 0.09-0.19) and PICCP tended to give a higher reading by between 0.09 and 0.19 mmHg overall. The limit of agreement was -1.74 to 2.02 overall.
CONCLUSIONS
These findings suggest that PICCP can be a reasonable alternative to CICCP in situations of dynamic systemic compliance and preload, as well as under stable hemodynamic conditions.

Keyword

CVP; Liver transplantation; Peripherally inserted central catheter pressure

MeSH Terms

Adult
Catheters
Central Venous Catheters
Central Venous Pressure
Compliance
Hemodynamics
Humans
Jugular Veins
Linear Models
Liver
Liver Transplantation
Reperfusion
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