Yonsei Med J.
2000 Apr;41(2):276-280. 10.3349/ymj.2000.41.2.276.
Liddle's syndrome: a report in a middle-aged woman
- Affiliations
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- 1Department of Internal Medicine, CHA General Hospital, College of Medicine, Pochon CHA Medical University, Sungnam, Korea. Kwonkh@cha.ac.kr
- KMID: 1758521
- DOI: http://doi.org/10.3349/ymj.2000.41.2.276
Abstract
- A 54-year-old woman with diabetes mellitus was hospitalized with generalized edema and weakness. She was also found to have hypertension, hypokalemia and metabolic alkalosis. Detailed examination showed subnormal plasma renin activity and plasma aldosterone concentration. Adrenal CT scanning revealed no adrenal tumor. A successful treatment with amiloride established the diagnosis of Liddle's syndrome for the patient. Liddle's syndrome, a rare hereditary disease usually found in young patients, should be considered in the differential diagnosis of hypertension even in elderly individuals.
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