Korean J Dermatol.
2004 Jan;42(1):77-79.
A Case of Metastatic Calcinosis Cutis
- Affiliations
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- 1Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. cse@snu.md
Abstract
- Metastatic calcinosis is a common feature of chronic renal failure. Its first manifestations are bone demineralization and non-visceral and/or visceral calcification with mostly mural deposits in arteries and arterioles. It is initially characterized by hyperphosphatemia followed by secondary or tertiary hyperparathyroidism. Cutaneous involvement is a rare complication. We present the case of 46-year-old man with end-stage renal disease accompanied by secondary hyperparathyroidism. He developed solitary erythematous nodule on the left first thumb and on tissue examination, there were small deposits of calcium in the dermis. His secondary hyperparathyroidism attributed to parathyroid multinodular hyperplasia was corrected by total parathyroidectomy and elevated laboratory abnormalities were normalized.
