Korean J Dermatol.  1982 Feb;20(1):9-13.

Comparison of Ampicillin with Procaine Penicillin in the Treatment of Male Gonorrhoea

• Han GC
• Kim JH

Abstract

A comparative investigation on the effect of ampicillin and procaine penicillin in the treatment of uncomplicated male gonorrhoea is presented. Three hundred and twenty eight male patients with uncomplicated gonococcal urethritis at a Venereal Disease Center in Seoul was subjected to this study. 164 patients were treated with 3.5 gm ampicillin plus l.0 gm probenecid, and 87 patients were followed. There were 16 (18.4%) failures and 15(21.1%) postgonococcal erethritis(PGU). Other 164 patients were treated with 4.8 million units produced penicillin plus 1.0gm prohenecid, and 73 patients were followed. There were 11 (15.1%) failures and 11(17.7%)PGU. There was no statistically significant difference of effect in the treatment of gonorrhoea between above two drugs. It is suggested that ampicillin plus probenecid is as effective as procaine penicilIin plus probenecid in the treatment of uncomplicated male gonococca1 urethritis.

MeSH Terms

Male
Humans