Yonsei Med J.  1994 Sep;35(3):245-251. 10.3349/ymj.1994.35.3.245.

Hematologic changes in acute carbon monoxide intoxication

• Lee SS
• Choi IS
• Song KS

• KMID: 1728908
• DOI: http://doi.org/10.3349/ymj.1994.35.3.245

Abstract

This study was performed to investigate the hematologic changes and its pathogenesis in acute carbon monoxide (CO) intoxication. Serial complete blood counts (CBC) were obtained in 17 patients with acute CO intoxication five times in two weeks. Peripheral blood smear, bone marrow aspiration and biopsy were obtained in 7 patients within the first week. We analyzed the results of serial CBC's. Levels of hemoglobin and hematocrit rose only initially, probably due to dehydration and hemoconcentration rather than hypoxia. Leukocytosis, mainly neutrophilic, observed during the first few days seemed to be a physiological phenomena due to a stressful situation, such as hypoxia. Levels of platelet increased steadily after a initial decrease. We found no specific findings in bone marrow.

Keyword

Acute carbon monoxide intoxication; RBC; WBC; platelet

MeSH Terms

Acute Disease
Adolescent
Adult
Aged
Biopsy
Blood Cell Count
Bone Marrow/pathology
Carbon Monoxide Poisoning/*blood/pathology
Female
Human
Male
Middle Age