Yonsei Med J.  2002 Feb;43(1):133-137. 10.3349/ymj.2002.43.1.133.

Two Primary Intracranial Tumors of Different Histology: Report of a Case with a Choroid Plexus Papilloma and a Concurrent Vestibular Schwannoma in the Cerebellopontine Angle

• Lee KS
• Seo EK

• KMID: 1726080
• DOI: http://doi.org/10.3349/ymj.2002.43.1.133

Abstract

A very rare case of multiple primary intracranial tumors is reported. A 41-year-old female patient was referred for surgery with a cerebellopontine angle (CPA) tumor. Medical history and MRI study showed typical findings of a right acoustic neuroma with a hydrocephalus. Neurological, dermatological, and ocular examinations revealed no evidence of neurofibromatosis. During surgery, a red-colored cauliflower like mass was found in the right CPA. The roof of the fourth ventricle could be seen through the lateral recess after removal of the tumor. Another mass, a 1.5-cm sized schwannoma protruding through the right internal auditory meatus, was removed by the transmeatal approach. Although the tumor masses were in contact and compressed against each other, there was a clear demarcation between them. Histological examination confirmed that the first mass was a typical choroid plexus papilloma with fibrovascular core, and that the second was a schwannoma. The patient recovered without any new neurological deficit. Result of a Medline search indicated that this rare combination of multiple primary tumors has not been reported previously.

Keyword

Multiple primary neoplasms; brain neoplasms; cerebellopontine angle; choroid plexus papilloma; acoustic neuroma

MeSH Terms

Adult
Case Report
Choroid Plexus Neoplasms/*pathology
Female
Human
Magnetic Resonance Imaging
Neoplasms, Multiple Primary/*pathology
Neurilemmoma/*pathology
Papilloma/*pathology
Vestibulocochlear Nerve Diseases/*pathology