Korean J Pathol.  2000 Jul;34(7):531-533.

Heterotopic Enchondral Ossification in Metastatic Colonic Adenocarcinoma: A case report

Affiliations
  • 1Department of Pathology, Seoul National University College of Medicine, Seoul 110-799, Korea

Abstract

Calcification and ossification of colon cancer is frequently encountered, especially in the mucinous carcinoma. However, cartilage formation or enchondral ossification has rarely been described in human colon cancer. This report describes a case of a 59-year-old man with retroperitoneal metastasis of mucinous adenocarcinoma of colon, which showed a widespread heterotopic ossification through membranous or enchondral ossification. The ossification appeared in apposition to tumor cell nests and in the organized mucin pool. In our knowledge, this is the first case showing enchondral ossification in gastrointestinal carcinoma in Korea.

Keyword

Colon; Mucinous adenocarcinoma; Heterotopic ossification; Enchondral ossification

MeSH Terms

Adenocarcinoma*
Adenocarcinoma, Mucinous
Cartilage
Colon*
Colonic Neoplasms
Humans
Korea
Middle Aged
Mucins
Neoplasm Metastasis
Ossification, Heterotopic
Mucins
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