Korean J Pathol.
2000 Jul;34(7):531-533.
Heterotopic Enchondral Ossification in Metastatic Colonic Adenocarcinoma: A case report
- Affiliations
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- 1Department of Pathology, Seoul National University College of Medicine, Seoul 110-799, Korea
Abstract
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Calcification and ossification of colon cancer is frequently encountered, especially in the
mucinous carcinoma. However, cartilage formation or enchondral ossification has rarely been
described in human colon cancer. This report describes a case of a 59-year-old man with
retroperitoneal metastasis of mucinous adenocarcinoma of colon, which showed a widespread
heterotopic ossification through membranous or enchondral ossification. The ossification appeared in
apposition to tumor cell nests and in the organized mucin pool. In our knowledge, this is the first
case showing enchondral ossification in gastrointestinal carcinoma in Korea.