Korean J Pathol.
1999 May;33(5):367-370.
Emphysematous Pyelonephritis in Diabetic Nephropathy A report of two cases
- Affiliations
-
- 1Department of Pathology, Yonsei University College of Medicine, Seoul 120-752, Korea.
Abstract
-
Diabetic nephropathy is characterized by one or a combination of the following
lesions: (1) glomerular involvement with three distinctive patterns: diffuse
glomerulosclerosis, nodular glomerulosclerosis, and exudative lesions; (2) arteriolo
sclerosis; (3) urinary tract bacterial infection with pyelonephritis and sometimes
emphysematous pyelonephritis. Emphysematous pyelonephritis is an uncommon
life-threatening and acute suppurative infection of the kidney, and usually occurs in
diabetic female patients. It is characterized by the production of intraparenchymal gas.
Glucose fermentation has been considered the main cause of the gas formation. We
presented two illustrative nephrectomy cases of emphysematous pyelonephritis in
addition to the typical pathologic features of diabetic nephropathy.