Korean J Pathol.  1997 Mar;31(3):269-274.

Intra-abdominal Angiosarcomatosis Induced by Irradiation

Affiliations
  • 1Department of Pathology, National Medical Center, Seoul 100-196, Korea.

Abstract

Therapeutic irradiation can induce angiosarcoma. Radiation-induced angiosarcoma constitutes 20% of all angiosarcomas. Although its common site of origin is the skin and subcutaneous tissue, it rarely arises in small or large bowels with a presentation as multifocal abdominal angiosarcomatosis. We report a case of intra-abdominal angiosarcomatosis involving the jejunum, ileum, transverse colon, mesentery and right ovary in a 63-year-old female. It developed 10 years after therapeutic irradiation for squamous cell carcinoma of uterine cervix. She developed panperitonitis due to intestinal perforation. She died from sepsis 3 days after segmental resection of the small bowel and right oophorectomy. We reviewed the previously reported cases and describe the clinicopathologic features of this tumor.

Keyword

Intra-abdominal angiosarcomatosis; Therapeutic irradiation

MeSH Terms

Carcinoma, Squamous Cell
Cervix Uteri
Colon, Transverse
Female
Hemangiosarcoma
Humans
Ileum
Intestinal Perforation
Jejunum
Mesentery
Middle Aged
Ovariectomy
Ovary
Sepsis
Skin
Subcutaneous Tissue
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