Korean J Pathol.  1997 Feb;31(2):93-99.

Congenital Anomalies Observed by Autopsies at the Seoul National University Children's Hospital

• Chung JH
• Seo JW
• Kim CJ
• Kim CW
• Chi JG

Abstract

A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.

Keyword

Congenital anomaly; Autopsy; Perinatal mortality; cardiovascular disease

MeSH Terms

Autopsy*
Cardiovascular Diseases
Cardiovascular System
Child
Humans
Incidence
Infant
Infant, Newborn
Musculoskeletal System
Nervous System
Parturition
Perinatal Mortality
Retrospective Studies
Seoul*