Korean J Pathol.  1995 Feb;29(1):122-125.

Pleomorphic Xanthoastrocytoma in a 58-year-old Woman: A case report

Affiliations
  • 1Department of Pathology, Chonbuk National University, Chonju, Korea.
  • 2Department of Pathology, Chonnam National University, College of Medicine, Chonju, Korea.

Abstract

A case of left parietal pleomorphic xanthoastrocytoma that occurred in a 58-year-old woman is reported clinicopathologically. Histopathologic diagnosis of pleomorphic xanthoastrocytoma was made because of the unique pleomorphic histologic features, positive glial fibrillary acidic protein in immunohistochemical staining. The flow cytometric analysis reveals DNA aneuploidy and relatively high S-phase fraction. The pleomorphic xanthoastrocytoma is considered as a special subgroup of glioma on the basis of superficial cortical location, GFAP expression, marked cellular atypia, xanthomatous cells, and relatively favorable prognosis.

Keyword

Pleomorphic xanthoastrocytoma; GFAP; Aneuploidy; Prognosis

MeSH Terms

Female
Humans
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