Korean J Otorhinolaryngol-Head Neck Surg.  2010 May;53(5):320-323. 10.3342/kjorl-hns.2010.53.5.320.

A Case of Aggressive Local Recurrence of Metastasizing Pleomorphic Adenoma with Multiple Lung Metastases

• Cho YJ
• Yang YS
• Lee EJ
• Hong KH

• KMID: 1722556
• DOI: http://doi.org/10.3342/kjorl-hns.2010.53.5.320

Abstract

Metastasizing pleomorphic adenoma is a rare condition of metastasis from a histologically benign salivary gland tumor. It usually occurs after multiple local recurrences, between 3 to 52 years after the occurrence of the primary lesion. No histologic or molecular parameters exist at the present time that could predict the development of metastasis in these neoplasms. Also, there is no definite treatment protocol available in cases of widespread metastasis. We report a case of metastasizing pleomorphic adenoma presenting with aggressive recurrence and multiple bilateral lung metastases that resulted despite surgery and chemotherapy. Clinical aspects of this disease is discussed.

Keyword

Pleomorphic adenoma; Metastasis; Neoplasm recurrence; Local

MeSH Terms

Adenoma, Pleomorphic
Clinical Protocols
Lung
Neoplasm Metastasis
Recurrence
Salivary Glands