Korean J Gastroenterol.  2011 Apr;57(4):237-242. 10.4166/kjg.2011.57.4.237.

Safety and Efficacy of Endoscopic Retrograde Cholangiopancreatograpy in Very Elderly Patients

Affiliations
  • 1Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Bundang, Korea. woltoong@snu.ac.kr

Abstract

BACKGROUND/AIMS
Endoscopic retrograde cholangiopancreatograpy (ERCP) is often used for the diagnosis and treatment of pancreaticobiliary diseases in the elderly patients. However, few studies have assessed its efficacy and safety in the very elderly. The purpose of this study was to evaluate the clinical outcomes of ERCP in the very elderly patients.
METHODS
Eight hundreds two patients who underwent ERCP at Seoul National University Bundang hospital were enrolled retrospectively. They were divided into three groups according to their ages (non-elderly group, elderly group and very-elderly group; <65, 65-79 and > or =80, respectively). The indications and clinical outcomes including the complications of ERCP were compared among groups.
RESULTS
The most common indication of ERCP was acute cholangitis in all the three groups. Periampullary diverticulum was more frequently observed in elderly and very-elderly patients than in younger patients. Mean duration of hospitalization was not different among three groups. ERCP success rate in all enrolled patients was approximately 90%, and there was no difference in terms of technical success rate between groups (p=0.1). However, the number of ERCP sessions was significantly higher in the very-elderly patients compared to in the non-elderly and elderly (1.38 vs. 1.13 and 1.18 respectively; p<0.001). There was no difference in mortality and complication rate between groups.
CONCLUSIONS
ERCP can be performed safely in very-elderly patients. Therefore, only age should not be regarded as one of the major determining factors whether to perform ERCP.

Keyword

ERCP; Elderly; Indication; Complication

MeSH Terms

Acute Disease
Age Factors
Aged
Aged, 80 and over
Cholangiopancreatography, Endoscopic Retrograde/adverse effects/*methods
Cholangitis/diagnosis
Common Bile Duct Diseases/diagnosis
Diverticulum/diagnosis
Female
Humans
Length of Stay
Male
Middle Aged
Pancreatic Diseases/*diagnosis/therapy
Retrospective Studies

Cited by  1 articles

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Tae Hoon Lee, Young Kyu Jung, Sang-Heum Park
Clin Endosc. 2014;47(4):334-340.    doi: 10.5946/ce.2014.47.4.334.


Reference

References

1. Sugiyama M, Atomi Y. Endoscopic sphincterotomy for bile duct stones in patients 90 years of age and older. Gastrointest Endosc. 2000; 52:187–191.
Article
2. Clarke GA, Jacobson BC, Hammett RJ, Carr-Locke DL. The indications, utilization and safety of gastrointestinal endoscopy in an extremely elderly patient cohort. Endoscopy. 2001; 33:580–584.
Article
3. Ashton CE, McNabb WR, Wilkinson ML, Lewis RR. Endoscopic retrograde cholangiopancreatography in elderly patients. Age Ageing. 1998; 27:683–688.
Article
4. MacMahon M, Walsh TN, Brennan P, Osborne H, Courtney MG. Endoscopic retrograde cholangiopancreatography in the elderly: a single unit audit. Gerontology. 1993; 39:28–32.
Article
5. Cotton PB, Lehman G, Vennes J, et al. Endoscopic sphincterotomy complications and their management: an attempt at consensus. Gastrointest Endosc. 1991; 37:383–393.
Article
6. Freeman ML, Nelson DB, Sherman S, et al. Complications of endoscopic biliary sphincterotomy. N Engl J Med. 1996; 335:909–918.
Article
7. Hacker KA, Schultz CC, Helling TS. Choledochotomy for calculous disease in the elderly. Am J Surg. 1990; 160:610–612.
Article
8. Siegel JH, Kasmin FE. Biliary tract diseases in the elderly: management and outcomes. Gut. 1997; 41:433–435.
Article
9. Sullivan DM, Hood TR, Griffen WO Jr. Biliary tract surgery in the elderly. Am J Surg. 1982; 143:218–220.
Article
10. Fritz E, Kirchgatterer A, Hubner D, et al. ERCP is safe and effective in patients 80 years of age and older compared with younger patients. Gastrointest Endosc. 2006; 64:899–905.
Article
11. Katsinelos P, Paroutoglou G, Kountouras J, Zavos C, Beltsis A, Tzovaras G. Efficacy and safety of therapeutic ERCP in patients 90 years of age and older. Gastrointest Endosc. 2006; 63:417–423.
Article
12. Lukens FJ, Howell DA, Upender S, Sheth SG, Jafri SM. ERCP in the very elderly: outcomes among patients older than eighty. Dig Dis Sci. 2010; 55:847–851.
Article
13. Keizman D, Ish Shalom M, Konikoff FM. Recurrent symptomatic common bile duct stones after endoscopic stone extraction in elderly patients. Gastrointest Endosc. 2006; 64:60–65.
Article
14. Kim DI, Kim MH, Lee SK, et al. Risk factors for recurrence of primary bile duct stones after endoscopic biliary sphincterotomy. Gastrointest Endosc. 2001; 54:42–48.
Article
15. Pereira-Lima JC, Jakobs R, Winter UH, et al. Longterm results (7 to 10 years) of endoscopic papillotomy for choledocholithiasis. Multivariate analysis of prognostic factors for the recurrence of biliary symptoms. Gastrointest Endosc. 1998; 48:457–464.
Article
16. Lillemoe KD. Pancreatic disease in the elderly patient. Surg Clin North Am. 1994; 74:317–344.
Article
17. Schmitz-Moormann P, Himmelmann GW, Brandes JW, et al. Comparative radiological and morphological study of human pancreas. Pancreatitis like changes in postmortem ductograms and their morphological pattern. Possible implication for ERCP. Gut. 1985; 26:406–414.
Article
18. Sofuni A, Maguchi H, Itoi T, et al. Prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis by an endoscopic pancreatic spontaneous dislodgement stent. Clin Gastroenterol Hepatol. 2007; 5:1339–1346.
Article
19. Ueki T, Otani K, Fujimura N, et al. Comparison between emergency and elective endoscopic sphincterotomy in patients with acute cholangitis due to choledocholithiasis: is emergency endoscopic sphincterotomy safe? J Gastroenterol. 2009; 44:1080–1088.
Article
20. Beaugerie L, Liguory C, Fritsch J, Choury A, Buffet C, Etienne JP. Lithiasis of the common bile duct in the aged subject treated with endoscopy (227 patients). Gastroenterol Clin Biol. 1988; 12:320–325.
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