Korean J Helicobacter Up Gastrointest Res.  2012 Sep;12(3):158-165. 10.7704/kjhugr.2012.12.3.158.

Gastrointestinal Lymphoma

• Lee YJ
• Lee JH

• KMID: 1716076
• DOI: http://doi.org/10.7704/kjhugr.2012.12.3.158

Abstract

Gastrointestinal tract is the most common location of extranodal lymphoma and 95.4% of gastrointestinal lymphoma is non-Hodgkin type. Although gastrointestinal lymphoma is usually secondary to nodal lymphoma, it can present as a primary gastrointestinal lymphoma with the majority being in the stomach (74.8%). In South Korea, the most frequent histological subtype of gastric lymphoma is extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), followed by diffuse large B-cell lymphoma. Gastrointestinal lymphoma typically presents with nonspecific symptoms, and endoscopic findings are quite variable. So, the diagnosis is mainly dependent on the histopathological evaluation. Treatment of gastrointestinal lymphoma is dictated primarily by the histopathological type and the stage of the disease. This review will discuss the histopathological classification, staging systems, clinical features and treatment of gastrointestinal lymphoma.

Keyword

Gastrointestinal neoplasms; Lymphoma

MeSH Terms

Gastrointestinal Neoplasms
Gastrointestinal Tract
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell
Lymphoma, B-Cell, Marginal Zone
Lymphoma, Non-Hodgkin
Republic of Korea
Stomach
Stomach Neoplasms
Lymphoma, Non-Hodgkin
Stomach Neoplasms