Korean J Parasitol.
1994 Mar;32(1):13-18. 10.3347/kjp.1994.32.1.13.
Promoting role of Clonorchis sinensis infection on induction of cholangiocarcinoma during two-step carcinogenesis
- Affiliations
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- 1Department of Parasitology, College of Medicine, Korea University, Seoul, Korea.
- KMID: 1715452
- DOI: http://doi.org/10.3347/kjp.1994.32.1.13
Abstract
- Chronic Clonorchis sinensis (CS) infection is etiologically related to cholangiocarcinoma (CHCA) in human and animals. This study was carried out to clarify the role of CS infection on dimethylnitrosamine (DMN)-induced cholangiocarcinogenesis. Fifteen hamsters were administered with 15 ppm DMN for 4 weeks and one week later, the hamsters were infected with 15 metacercariae of CS (DMN--
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