J Korean Med Sci.  2007 Apr;22(2):362-364. 10.3346/jkms.2007.22.2.362.

Vaccine-associated Paralytic Poliomyelitis: A Case Report of Flaccid Monoparesis after Oral Polio Vaccine

• Kim SJ
• Kim SH
• Jee YM
• Kim JS

• KMID: 1713202
• DOI: http://doi.org/10.3346/jkms.2007.22.2.362

Abstract

This report describes a case of acute flaccid paralysis after administration of oral polio vaccine (OPV). A 4 month-old male patient with the decreased movement of left lower extremity for 1 month was transferred to the Department of Pediatrics. He received OPV with DTaP at 2 months of age. Flaccid paralysis was detected 4 weeks after OPV immunization. Attempts to isolate Sabin-like viruses in the two stool and CSF samples failed because those specimens were collected more than 2 month after the onset of paralysis. Hypotonic monoparesis (GIV/V), hypotonia and atrophy on the left lower extremity, and ipsilateral claw foot persisted for more than 18 months, while we followed him with rehabilitation therapy. This is the first case of officially approved, recipient vaccine-associated paralytic poliomyelitis in Korea.

Keyword

Poliovirus vaccine, Poliomyelitis

MeSH Terms

Poliovirus Vaccine, Oral/*adverse effects
Poliomyelitis/*chemically induced/diagnosis/rehabilitation
Paraplegia/*chemically induced/diagnosis/rehabilitation
Male
Infant
Humans

Figure

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  Fig. 1 Simple radiography with weight bearing showed left side claw foot deformity.

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