J Agric Med Community Health.  2014 Mar;39(1):25-36.

The Relationship between Coronary Risk Factors and Coronary Calcium Score Detected by Computed Tomography Coronary Angiography in Korean Middle Aged Men

Affiliations
  • 1Department of Occupational & Environmental Medicine, Samsung Changwon Hospital, College of Medicine, Sungkyunkwan University, Korea.
  • 2Department of Preventive Medicine, School of Medicine, Gyeongsang National University & Institute of Health Sciences, Korea. jjbkkr@yahoo.co.kr
  • 3Department of Internal Medicine, School of Medicine, Gyeongsang National University & Institute of Health Sciences, Korea.

Abstract


OBJECTIVES
The objective of this study was to investigate the relationship between coronary artery calcification and risk factors of cardiovascular disease with multidetector computed tomography.
METHODS
Data were collected from 5,899 males between 30 and 59 years old by interview, survey, physical examination, blood test, and multidetector computed tomography in the university hospital from January 2010 to December 2011. We confirmed the coronary artery calcium scores of subjects by multidetector computed tomography and identified risk factors of cardiovascular disorders. We investigated the relationship between coronary artery calcification and risk factors of cardiovascular disorders.
RESULTS
Mean calcium score of the coronary arteries in 5,899 participants was 8.20, and 773 participants (13.1%) exhibited coronary artery calcification. The presence of coronary artery calcification was correlated to risk factors of cardiovascular disease (age, blood pressure, triglyceride, HDL cholesterol, LDL cholesterol, glucose, Apolipoprotein A-1, Apolipoprotein B, body mass index, waist circumference) and risk assessment tools of cardiovascular disorders. Significant predicted factors of coronary artery calcification had different patterns in each age group (30-39, 40-49, 50-59 years old).
CONCLUSIONS
We confirmed the relationship between coronary artery calcification and either typical risk factors of cardiovascular disease or risk assessment tools of cardiovascular disease. In addition, we also observed that the pattern of these factors varied according to age. Therefore, age-related variation needs to be considered in management strategies to prevent cardiovascular disease.

Keyword

Cardiovascular disease; Multidetector computed tomography; Vascular calcification
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