The Assessment of Carfecillin in Acute Uncomplicated Urinary Tract Infection

Kim, Je Jong; Koh, Sung Kun

Abstract

Fifty cases of acute uncomplicated urinary tract infection were selected and 3.0gm of Carfecillin was given for one day in two doses. The clinical and bacteriological results were compared with the results of 32 cases of the urinary tract infection who was given 200 mg of Doxycycline daily for 7 days. Of 50 patients receiving Carfecillin only 23 cases were sensitive to Carfecillin though 32 patients receiving Doxycycline were all sensitive to Doxycycline on prior to treatment urine culture. Carfecillin was effective in 34 cases among 38 cases of cystitis while Doxycycline was effective in 12 cases among 21 cases of cystitis. In 7 out of 12 cases of pyelonephritis Carfecillin was effective, while Doxycycline was effective in 9 out of 11 cases. Among 23 cases which were sensitive to Carfecillin, Carfecillin single day treatment was effective in 13 out of 17 cases of cystitis and 4 out of 6 cases of pyelonephritis. Both Carfecillin and Doxycycline showed good efficacy to E-coli, Staphylococcus aureus, Klebsiella, Streptococcus and Enterobacter. A single day treatment of Carfecillin was as effective as a conventional treatment of Doxycycline for the treatment of uncomplicated urinary tract infections.