Total Protein and Paper Electrophoretic Fractions of the Serum of Syphilitic Patients

Im, Byung Sung; Lim, S H

Abstract

Many reports have been found in the literature regarding the electrophoretic study of various urogenital diseases, but those on syphilis are relatively rare. It is author's opinion that the correlation between syphilis and the dysfunction of various organs must also be elucidated into detail. On this view point the author has studied the total protein and paper electrophoretic fractions of the serum derived from the patients of syphilis in 17 males and 5 females visited our department during the period from October, 1962 to September, 1964 Age distribution was between 18 and 45 years of age and duration of history was from 3 months to 8 months. The results obtained were as follows: 1. Total protein and electrophoretic fractions of 22 patients' serum: a) The amount of total protein decreased slightly. b) Albumin decreased markedly. c) Alpha 1 globulin decreased remarkably. d) Alpha 2 globulin decreased slightly. e) Beta globulin increased very remarkably. f) Gamma globulin increased markedly. g) A/G ratio decreased very remarkably. All of the above patterns were compared with normal rate. 2. Total protein and electrophoretic fractions of same 22 patients' serum in duration 30 days after complete therapy: a) The amount of total protein, albumin alpha 2 globulin, gamma globulin and A/G ratio etc. are unchanged b) Alpha 1 globulin decreased markedly. c) Beta globulin increased slightly. All of the above pattern were compared with normal rate.