Korean J Dermatol.  1985 Dec;23(6):769-773.

Investigation of Cell Mediated Immunity in Patients with Behcet's Syndrome, Using the DNCB Sensitization

• Bang DS
• Lee SN
• Kim DH
• Nam IW

Abstract

Various immunologic investigations of 159 patients with Behqets syndrome undertaken included; the DNCB sensitization test, total T-cells and T-cell subsets and the lymphocyte transformation test using PHA. The percentage of positive esponsiveness to DNCB decreased in the order of possible (65%), suspected (60%), incomplete (37%) and complete type (37%), The number of patients with impaired LTT was larger in the group of patients with DNCB( + ) responsiveness (seventeen of 32) than in DNCB(+) group (six of 25), There was significant impairment of cell mediated immunity in Behcets syndrome compared to normal subjects, when analyzed by the impaired LTT and decreased proportions of helper T-cells.

Keyword

Behcet's syndrome; DNCB sensitization

MeSH Terms

Behcet Syndrome*
Dinitrochlorobenzene*
Humans
Immunity, Cellular*
Lymphocyte Activation
T-Lymphocyte Subsets
T-Lymphocytes
T-Lymphocytes, Helper-Inducer
Dinitrochlorobenzene