Korean J Dermatol.  1985 Jun;23(3):290-298.

Effects of Topical Anti-inflammatory Agents and Emollients on UVB Erythema and Pigmentation in Normal Korean Males

• Park YK
• Baek SE

Abstract

In healthy Korean adult males, 6 hour-MED was 51 2+22.6mJ/cm,24 hour-MED was 67. 5+26. 7mJ/cm, and MMD was 86. 5 t21. 3mJ/cm for UVB irradiation respectively. UVB-MED and UVB-MMD was increased by desoxymethasone, hydrocortisone, and bufexama.c creams. Hydrophilic ointment base increased only 24 hour-MED. For 1 MED of UVB, all test agents inhibited erytherna for 48 hours, For 2 MEDs of UVB, desoxymethasone, bufexamac; and hydrocortisone creams inhibited erythema at 6 hours, while desoxymethasone and hydrophilic ointment base could suppress erythema at: 24. hours after irradiation. However, desoxymethasone was the most effective. Hydrophilic ointment base was efficacious only at 24 hours after irradiation. For 1 MMD of UVB, desoxymethasone, hydrocortisone, and bufexamac creams could reduced the delayed tanning (DT) reaction.

Keyword

UVB; Corticosteroid; MED; MMD290

MeSH Terms

Adult
Anti-Inflammatory Agents*
Bufexamac
Desoximetasone
Emollients*
Erythema*
Humans
Hydrocortisone
Male*
Pigmentation*
Tanning
Triacetoneamine-N-Oxyl
Anti-Inflammatory Agents
Bufexamac
Desoximetasone
Emollients
Hydrocortisone
Triacetoneamine-N-Oxyl