Korean J Dermatol.  1982 Aug;20(4):597-603.

A Case of Xanthoma Tuberosum in Type II Hyperlipoproteinemia

• Han EH
• Kwon KS
• Chung TA

Abstract

A 22-year-old male has had multiple, grouped, asymptomatic, yellowish flat papules, nodules, and plaques on the knees, elbows, butteeks, hands, and feet. Yellowish nodules first appeared on the heels after birth, and gradually increased in size and number and spread to the knees, elbows, buttocks, and hands. Physical examination revealed normaI except for the skin lesions. Gross finding of the serum was clear and paper electrophoresis revealed marked increase in betalipo-protein and mild increase in prebetalipoprotein, suggesting type II hyperlipoproteinemia Serum cholesterol was 510 mg%, and serum triglyceride was 190mg%. Histopathology showed many aggregates of foam cells on H-E stain and many lipid droplets in the dermis on oil red O stain.

MeSH Terms

Buttocks
Cholesterol
Dermis
Elbow
Electrophoresis, Paper
Foam Cells
Foot
Hand
Heel
Humans
Hyperlipoproteinemia Type II*
Knee
Male
Parturition
Physical Examination
Skin
Triglycerides
Xanthomatosis*
Young Adult
Cholesterol