Korean J Dermatol.
1982 Apr;20(2):335-339.
A Fatal Case of Weber-Christian Disease
Abstract
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Weber-Christian diaease is characterized by recurrent crops of subcutaneous nodules or plaques which occur during febrile periods and usually has spontaneous regression. Since the earlier case reports there have been instances of nodular panniculitis affecting visceral fat as well as the subcutaneous tissue. Death may rarely occur follow ing visceral involvement. We experienced a fatal case of Weber-Christian disease in a 32 year old female, who had prominent hepatomegaly and leukopenia accompanied by various general symptoms such as nausea, vomiting, abdominal pain, and cough. This case also had unusually large erythematous swelling of the face and aMomen in addition to multiple subcutaneous nodules in the extremities and trunk.