Korean J Dermatol.  1981 Dec;19(6):963-967.

Disseminated Superficial ACtinic Porokeratosis Occuring in 3 Generations

• Chung EJ
• Kim TY
• Kim HO
• Kim CW
• Houh W

Abstract

Disseminated superficial actinic porokeratosis (DSAP) has an autosomal dominant mode of inheritance with reduced penetration at young age, characterized by multiple superficial keratotic lesions surrounded by a slightly raised border. The aggrevation of the lesion by exposing UV light indicates that phenotypic expression of gene regluating DSAP is related to sun light. We observed a family of which 13 members had DSAP in 3 successive generations. They were grandrnother, two sons of her 3 offsprings, 2 grandsons and 8 granddaughters. Lesions of all cases were found on the sun exposed areas, especially, face, extremities and upper trunk but exceptionally one had a lesion on the unex posed area, abdomen below the iliac crest. The number of lesions of the individual patient were 12-116, and there appeared to be increasing number of lesions with age.

MeSH Terms

Abdomen
Extremities
Family Characteristics*
Humans
Porokeratosis*
Solar System
Ultraviolet Rays
Wills