Korean J Dermatol.
1980 Jun;18(3):219-225.
Bowen's Disease Associated with cutaneous Horn and Squamous Cell Carcinoma
Abstract
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Bowen's disease is intraepidermal squamous cell carcinoma involving skin and certain mucocutaneous junctions. The disease usually persues a slow relatively benign course but may progress to invasive squamous cell carcinoma. The present case, 67-years-old male, showed multiple dark brownish somewhat elevated horny lesions on the trunk and extremities including both palms. Some of the lesions had the appearance of small horns. Multiple biopsy specimens revealed typical histological findings of Bowen's disease or frank invasive squamous cell carcinoma. according to the each biopsy site. Authors treated all the lesions with surgical avulsion and electrodesiccation with curettage under general anestthesia and subsequent topical 5-FU ointment application.