Korean Circ J.  1985 Dec;15(4):665-669. 10.4070/kcj.1985.15.4.665.

Efficacy of Sublingual Nifedipine(Adalat(R)) in Hypertensive Emergencies

• Choi SK
• Kim MH
• Kim NH
• Lee JK
• Yoo WS

• KMID: 1677321
• DOI: http://doi.org/10.4070/kcj.1985.15.4.665

Abstract

The effects of sublingual nifedipine were assessed in 20 patients with severe hypertension in emergency room setting. Sublingual nifedipine 10mg significantly reduced the systolic and diastolic blood pressures from 15 minutes after administration in all patients. The maximal lowering effects were seen at 1 and half hour after administration(45.3/34.3mmHg, 22%/27%). Heart rate did not change significantly except mild increase in 45 and 60 minutes after administration. No serious unwanted effects were observed. Nifedipine is a simple, effective and safe alternative drug for managing hpertensive emergencies especially in general practice or small sized emergency rooms.

MeSH Terms

Emergencies*
Emergency Service, Hospital
General Practice
Heart Rate
Humans
Hypertension
Nifedipine
Nifedipine