Korean J Dermatol.  1976 Sep;14(3):261-267.

Two Cases of Bullous Dermatoses in Childhood

• Lee CH
• Lee CW
• Lee YS

Abstract

We presented two cases of bullous dermatoses in childhood. The first case was a 13-year-old boy who had numerous tense bullae on the scalp, both forearms and dorsa of hands, trunk and both thighs in symmetrical distribution, but he had not any oral lesion. On histologic examination, subepidermal bullae containing many neutrophils and only a few eosinophils were demonstrated. The lesions began to subside prornptly since 2 days after ornl administration of prednisolone and there was no evidence of recurrence during the follow-up studies of 4 months. The second case was a 14-year-old boy who had erythematous macules, vesicles, bullae and crusts scattered irregularly on almost entire body surface and had some oral lesions. Histologically erythematous macular lesions revealed many microabscesses composed almost entirely oi neutrophils on the tip of dermal papillae but vesicular lesions showed intraepidermal bulla containing numerous eosinophils exclusively. His skin lesions were well suppressed by DDS but reappeared one or two days after cessation of DDS. We thought these two cases were not the typical cases of bullous pemphigoid or dermatitis herpetiforrnis. We did not perform immunologic studies, so we cannot assure that these two cases were belong to either bullous pemphigoid or dermatitis herpetiformis and the so-called benign chronic bullous dermatosis of childhood.

MeSH Terms

Adolescent
Dermatitis
Dermatitis Herpetiformis
Eosinophils
Follow-Up Studies
Forearm
Hand
Humans
Male
Neutrophils
Pemphigoid, Bullous
Prednisolone
Recurrence
Scalp
Skin
Skin Diseases
Skin Diseases, Vesiculobullous*
Thigh
Transcutaneous Electric Nerve Stimulation
Prednisolone