Korean J Dermatol.
1975 Jun;13(2):125-129.
Preribial Myxedema
Abstract
- Pretibial myxedema is a rare condition whieh may occur following the active or treated hyperthyroidism. The preeise cause of pretibial myxedema is not known, but it is now established the Long Acting Thyroid Stimulator(LATS) is 7S-gammaglobulin, that it is present in the serum of 80% of patients with hyperthyroidism and that its activity is as being an autoantibody against a thyroid antigen, retroorbital tissues and in the skin. A 28-year old pregnant housewife was well until age 24 when she developed hyperthyroidism with swelling of the thyroid gland, exopbthalmos and clubbing of the fingers. She was treated with subtotal thyroidectomy 2 years ago at other clinic. The skin lesions revealed circumscribed, firm, and elevated nodules with excess hair growth on shin and dorsum of feet since their onset of one and half years to visit to our hospital. The hiatologic findings showed considerable amounts of mucin especially in the midportion of the dermis. The leaions were improved by the local application of 0.01% Fluocinolone acetonide(Synalar') ointment with occlusive dressing technique.
